Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
3R01DC002058-04A1S1
Application #
2697628
Study Section
Hearing Research Study Section (HAR)
Project Start
1993-07-01
Project End
2002-06-30
Budget Start
1997-12-15
Budget End
1998-06-30
Support Year
4
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Chicago
Department
Neurology
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Holt, J Chris; Jordan, Paivi M; Lysakowski, Anna et al. (2017) Muscarinic Acetylcholine Receptors and M-Currents Underlie Efferent-Mediated Slow Excitation in Calyx-Bearing Vestibular Afferents. J Neurosci 37:1873-1887
Contini, Donatella; Price, Steven D; Art, Jonathan J (2017) Accumulation of K+ in the synaptic cleft modulates activity by influencing both vestibular hair cell and calyx afferent in the turtle. J Physiol 595:777-803
Liu, Xiao-Ping; Wooltorton, Julian R A; Gaboyard-Niay, Sophie et al. (2016) Sodium channel diversity in the vestibular ganglion: NaV1.5, NaV1.8, and tetrodotoxin-sensitive currents. J Neurophysiol 115:2536-55
Gatto, Rodolfo G; Chu, Yaping; Ye, Allen Q et al. (2015) Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease. Hum Mol Genet 24:5285-98
Holt, J Chris; Kewin, Kevin; Jordan, Paivi M et al. (2015) Pharmacologically distinct nicotinic acetylcholine receptors drive efferent-mediated excitation in calyx-bearing vestibular afferents. J Neurosci 35:3625-43
Goldberg, Jay M; Holt, Joseph C (2013) Discharge regularity in the turtle posterior crista: comparisons between experiment and theory. J Neurophysiol 110:2830-48
Dalet, Antoine; Bonsacquet, Jeremie; Gaboyard-Niay, Sophie et al. (2012) Glutamate transporters EAAT4 and EAAT5 are expressed in vestibular hair cells and calyx endings. PLoS One 7:e46261
Schraven, Sebastian P; Franz, Christoph; Ruttiger, Lukas et al. (2012) Altered phenotype of the vestibular organ in GLAST-1 null mice. J Assoc Res Otolaryngol 13:323-33
Lysakowski, Anna; Gaboyard-Niay, Sophie; Calin-Jageman, Irina et al. (2011) Molecular microdomains in a sensory terminal, the vestibular calyx ending. J Neurosci 31:10101-14
Goldberg, Jay M; Cullen, Kathleen E (2011) Vestibular control of the head: possible functions of the vestibulocollic reflex. Exp Brain Res 210:331-45

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