Autistic Spectrum Disorders (ASD) form a group of neuropsychiatric conditions whose core behavioral features include impairments in reciprocal social interaction, in communication, and repetitive, stereotyped, or restricted interests and behaviors. The importance of prosodic deficits in the adaptive communicative competence of speakers with ASD, as well as for a fuller understanding of the social disabilities central to these disorders is generally recognized; yet current studies are few in number and have significant methodological limitations. The objective of the proposed project is to detail prosodic deficits in young speakers with ASD through a series of experiments that address these disabilities and related areas of function. Key features of the project include: 1) the application of innovative technology. The study will apply computer-based speech and language technologies for quantifying expressive prosody, for computing dialogue structure, and for generating acoustically controlled speech stimuli for measuring receptive prosody; moreover, all experiments will be delivered via computer to insure consistency of stimuli and accuracy of recording responses; 2) broad coverage of the dimensions of prosody. All three functions of prosody, grammatical, pragmatic, and affective, will be addressed; expressive and receptive tasks are included; and both contextualized tasks (dialogue, story comprehension and memory) and decontextualized tasks (e.g., vocal affect recognition) will be used; 3) inclusion of neuropsychological assessment and classification methodologies to address within-group heterogeneity and obtain a detailed characterization of the groups; 4) inclusion of two comparison groups: children with typical development and those with Developmental Language Disorder; 5) inclusion of an experimental treatment program to enhance the prosodic abilities of speakers with ASD.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC007129-03
Application #
7162988
Study Section
Language and Communication Study Section (LCOM)
Program Officer
Cooper, Judith
Project Start
2005-01-10
Project End
2009-12-31
Budget Start
2007-01-01
Budget End
2007-12-31
Support Year
3
Fiscal Year
2007
Total Cost
$550,594
Indirect Cost
Name
Oregon Health and Science University
Department
Engineering (All Types)
Type
Schools of Medicine
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
MacFarlane, Heather; Gorman, Kyle; Ingham, Rosemary et al. (2017) Quantitative analysis of disfluency in children with autism spectrum disorder or language impairment. PLoS One 12:e0173936
Gorman, Kyle; Olson, Lindsay; Hill, Alison Presmanes et al. (2016) Uh and um in children with autism spectrum disorders or language impairment. Autism Res 9:854-65
Hill, Alison Presmanes; van Santen, Jan; Gorman, Kyle et al. (2015) Memory in language-impaired children with and without autism. J Neurodev Disord 7:19
Gorman, Kyle; Bedrick, Steven; Kiss, Géza et al. (2015) Automated morphological analysis of clinical language samples. Proc Conf 2015:108-116
Rouhizadeh, Masoud; Prud'hommeaux, Emily; van Santen, Jan et al. (2015) Measuring idiosyncratic interests in children with autism. Proc Conf Assoc Comput Linguist Meet 2015:212-217
Rouhizadeh, Masoud; Sproat, Richard; van Santen, Jan (2015) Similarity Measures for Quantifying Restrictive and Repetitive Behavior in Conversations of Autistic Children. Proc Conf 2015:117-123
Prud'hommeaux, Emily; Morley, Eric; Rouhizadeh, Masoud et al. (2014) COMPUTATIONAL ANALYSIS OF TRAJECTORIES OF LINGUISTIC DEVELOPMENT IN AUTISM. SLT Workshop Spok Lang Technol 2014:266-271
van Santen, Jan P H; Sproat, Richard W; Hill, Alison Presmanes (2013) Quantifying repetitive speech in autism spectrum disorders and language impairment. Autism Res 6:372-83
Shriberg, Lawrence D; Paul, Rhea; Black, Lois M et al. (2011) The hypothesis of apraxia of speech in children with autism spectrum disorder. J Autism Dev Disord 41:405-26
Van Santen, Jan P H; Prud'hommeaux, Emily Tucker; Black, Lois M et al. (2010) Computational prosodic markers for autism. Autism 14:215-36

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