In everyday life, humans are regularly exposed to and must make sense of complex acoustical sounds in their environment. While many hearing aid (HA) and cochlear implant (CI) users enjoy fairly accurate speech perception in quiet, they often experience difficulties when listening to more spectrally complex stimuli, such as music, a pervasive and culturally significant art form, and speech in background noise. These limitations are likely related to the signal processing of CIs as well as limitations in the central auditory pathways, particularly in pediatric populations with congenital hearing loss. Through investigation of complex acoustic signals at the auditory periphery, and the coding of those stimuli within the central auditory nervous system, we will deepen our understanding of why music and speech perception in noise is so challenging for hearing impaired listeners. In this study, we will investigate characteristics of the listener's auditory system, the acoustic signal input, as well as potential benefit of music training in relation to perception of spectrally complx sounds (music and speech in background noise). Our first specific aim defines the relationship between cortically generated evoked potentials, the acoustic change response, and perceptual measures of complex stimuli for a wide range of listeners, including normal hearing listeners, hearing aid users and CI recipients.
In Aim 2, through within-subject comparisons, we will measure the effect that different CI signal inputs have on higher level processing of spectrally complex sounds within the auditory nervous system.
Aim 3, which focus on the role of experience-dependent plasticity in perception, investigate the impact of musical training on evoked potentials and perception of music and of speech in background noise. These studies will help us to evaluate the relative benefits of specific training parameters for groups of CI recipients who vary in important factors (e.g., age, hearing profile and history), and will help us predict which individuals may benefit most from systematic training. In summary, these results could (a) expand our understanding of factors that impact perception of spectrally complex signals, (b) investigate benefits of musical training, (c) determine the extent to which training can be generalized to other tasks, like perception of speech in noise, and (d) lead to the development of more effective rehabilitation strategies.

Public Health Relevance

This research will (a) improve our understanding of how complex sounds such as music and speech in noise are processed within the auditory system of hearing aid and cochlear implant users, and (b) evaluate interventions designed to improve their perception of these spectrally complex signals. We will do this by examining how (and whether) participation in music-based auditory training programs enhance perception and enjoyment of music and whether or not they generalize to perception of speech in noise. Results may lead to the development of more effective rehabilitation strategies for HA and CI users.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC012082-03
Application #
8699751
Study Section
Auditory System Study Section (AUD)
Program Officer
Donahue, Amy
Project Start
2012-08-01
Project End
2015-07-31
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Iowa
Department
Other Health Professions
Type
Schools of Arts and Sciences
DUNS #
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Brown, Carolyn J; Jeon, Eun-Kyung; Driscoll, Virginia et al. (2017) Effects of Long-Term Musical Training on Cortical Auditory Evoked Potentials. Ear Hear 38:e74-e84
Tejani, Viral D; Abbas, Paul J; Brown, Carolyn J (2017) Relationship Between Peripheral and Psychophysical Measures of Amplitude Modulation Detection in Cochlear Implant Users. Ear Hear 38:e268-e284
Abbas, Paul J; Tejani, Viral D; Scheperle, Rachel A et al. (2017) Using Neural Response Telemetry to Monitor Physiological Responses to Acoustic Stimulation in Hybrid Cochlear Implant Users. Ear Hear 38:409-425
Sjoberg, Kristin M; Driscoll, Virginia D; Gfeller, Kate et al. (2017) The impact of electric hearing on children's timbre and pitch perception and talker discrimination. Cochlear Implants Int 18:36-48
Gfeller, K (2016) Music-based training for pediatric CI recipients: A systematic analysis of published studies. Eur Ann Otorhinolaryngol Head Neck Dis 133 Suppl 1:S50-6
Driscoll, Virginia D; Welhaven, Anne E; Gfeller, Kate et al. (2016) Music Perception of Adolescents Using Electroacoustic Hearing. Otol Neurotol 37:e141-7
Kashio, Akinori; Tejani, Viral D; Scheperle, Rachel A et al. (2016) Exploring the Source of Neural Responses of Different Latencies Obtained from Different Recording Electrodes in Cochlear Implant Users. Audiol Neurootol 21:141-9
Scheperle, Rachel A; Abbas, Paul J (2015) Peripheral and Central Contributions to Cortical Responses in Cochlear Implant Users. Ear Hear 36:430-40
Kirby, Benjamin James; Brown, Carolyn J (2015) Effects of Nonlinear Frequency Compression on ACC Amplitude and Listener Performance. Ear Hear 36:e261-70
Whipple, Christina M; Gfeller, Kate; Driscoll, Virginia et al. (2015) Do communication disorders extend to musical messages? An answer from children with hearing loss or autism spectrum disorders. J Music Ther 52:78-116

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