Recent studies have documented increased prevalence of dental fluorosis in the United States and Canada due to widespread ingestion of fluoride during tooth development, both from fluoride used for caries prevention and from water, beverages and foods. In this study, longitudinal assessment of dietary and non-dietary fluoride exposures will continue using previously collected data, and from continued data collection at 6-month intervals, on a birth cohort aged 73-107 months at the beginning of the proposed renewal. Parents will continue to provide detailed data on their children's fluoride exposures and ingestion via written questionnaires and 3-day dietary diaries. Composite indices of fluoride intake will be obtained. Dental fluorosis and caries prevalence and severity in the mixed dentition will be assessed at age 8 1/2 to 9. Primary specific aims are to: 1) continue to assess dietary and non-dietary fluoride exposures, 2a) determine the prevalence and severity of dental fluorosis in the early erupting permanent dentition, 2b) assess relationships between early-erupting permanent tooth dental fluorosis and longitudinally recorded fluoride exposures and ingestion levels, and 3) assess the relationships between the prevalence and severity of dental fluorosis of the early-erupting permanent dentition and the prevalence and severity of fluorosis of the primary dentition.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE009551-11
Application #
6634620
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Program Officer
Harris, Emily L
Project Start
1991-09-01
Project End
2005-03-31
Budget Start
2003-04-01
Budget End
2004-03-31
Support Year
11
Fiscal Year
2003
Total Cost
$605,678
Indirect Cost
Name
University of Iowa
Department
Dentistry
Type
Schools of Dentistry
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Kwon, Soyang; Janz, Kathleen F; Letuchy, Elena M et al. (2017) Association between body mass index percentile trajectories in infancy and adiposity in childhood and early adulthood. Obesity (Silver Spring) 25:166-171
Ballantine, Jami L; Carlson, Jenna C; Ferreira Zandonรก, Andrea G et al. (2017) Exploring the genomic basis of early childhood caries: a pilot study. Int J Paediatr Dent :
Warren, John J; Van Buren, John M; Levy, Steven M et al. (2017) Dental caries clusters among adolescents. Community Dent Oral Epidemiol 45:538-544
Eckert, Scott; Feingold, Eleanor; Cooper, Margaret et al. (2017) Variants on chromosome 4q21 near PKD2 and SIBLINGs are associated with dental caries. J Hum Genet 62:491-496
Marshall, Teresa A; Van Buren, John M; Warren, John J et al. (2017) Beverage Consumption Patterns at Age 13 to 17 Years Are Associated with Weight, Height, and Body Mass Index at Age 17 Years. J Acad Nutr Diet 117:698-706
Janz, Kathleen F; Boros, Piroska; Letuchy, Elena M et al. (2017) Physical Activity, Not Sedentary Time, Predicts DXA-Measured Adiposity Age 5-19 Years. Med Sci Sports Exerc :
VanBuren, John; Cavanaugh, Joseph; Marshall, Teresa et al. (2017) AIC identifies optimal representation of longitudinal dietary variables. J Public Health Dent 77:360-371
Bhagavatula, Pradeep; Levy, Steven M; Broffitt, Barbara et al. (2016) Timing of fluoride intake and dental fluorosis on late-erupting permanent teeth. Community Dent Oral Epidemiol 44:32-45
Lorenz, Douglas J; Levy, Steven; Datta, Somnath (2016) Inferring marginal association with paired and unpaired clustered data. Stat Methods Med Res :
Kwon, Soyang; Janz, Kathleen F; Letuchy, Elena M et al. (2016) Parental characteristic patterns associated with maintaining healthy physical activity behavior during childhood and adolescence. Int J Behav Nutr Phys Act 13:58

Showing the most recent 10 out of 138 publications