Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK033665-11S1
Application #
653389
Study Section
Pathology A Study Section (PTHA)
Project Start
1995-02-03
Project End
1995-11-30
Budget Start
1995-02-03
Budget End
1995-11-30
Support Year
11
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Rahman, Md Mizanur; El Jamali, Amina; Halade, Ganesh V et al. (2018) Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling. Oxid Med Cell Longev 2018:6054361
Shi, Qian; Viswanadhapalli, Suryavathi; Friedrichs, William E et al. (2018) Nox4 is a Target for Tuberin Deficiency Syndrome. Sci Rep 8:3781
Shanmugasundaram, Karthigayan; Nayak, Bijaya K; Friedrichs, William E et al. (2017) NOX4 functions as a mitochondrial energetic sensor coupling cancer metabolic reprogramming to drug resistance. Nat Commun 8:997
Lee, Hak Joo; Lee, Doug Yoon; Mariappan, Meenalakshmi M et al. (2017) Hydrogen sulfide inhibits high glucose-induced NADPH oxidase 4 expression and matrix increase by recruiting inducible nitric oxide synthase in kidney proximal tubular epithelial cells. J Biol Chem 292:5665-5675
Gorin, Yves (2016) The Kidney: An Organ in the Front Line of Oxidative Stress-Associated Pathologies. Antioxid Redox Signal 25:639-641
Eid, St├ęphanie; Boutary, Suzan; Braych, Kawthar et al. (2016) mTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes. Antioxid Redox Signal 25:703-719
Nayak, Bijaya K; Shanmugasundaram, Karthigayan; Friedrichs, William E et al. (2016) HIF-1 Mediates Renal Fibrosis in OVE26 Type 1 Diabetic Mice. Diabetes 65:1387-97
Thameem, Farook; Voruganti, V Saroja; Blangero, John et al. (2015) Evaluation of neurotrophic tyrosine receptor kinase 2 (NTRK2) as a positional candidate gene for variation in estimated glomerular filtration rate (eGFR) in Mexican American participants of San Antonio Family Heart study. J Biomed Sci 22:23
Gorin, Yves; Wauquier, Fabien (2015) Upstream regulators and downstream effectors of NADPH oxidases as novel therapeutic targets for diabetic kidney disease. Mol Cells 38:285-96
Souto Padron de Figueiredo, Alvaro; Salmon, Adam B; Bruno, Francesca et al. (2015) Nox2 mediates skeletal muscle insulin resistance induced by a high fat diet. J Biol Chem 290:13427-39

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