Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK043652-11
Application #
6517207
Study Section
Reproductive Endocrinology Study Section (REN)
Program Officer
Sato, Sheryl M
Project Start
1991-06-01
Project End
2005-05-31
Budget Start
2002-06-01
Budget End
2003-05-31
Support Year
11
Fiscal Year
2002
Total Cost
$292,626
Indirect Cost

  Institution

Name
University of Alabama Birmingham
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294

  Publications

Wu, Jing; Bowe, Damon B; Sadlonova, Andrea et al. (2014) O-GlcNAc transferase is critical for transducin-like enhancer of split (TLE)-mediated repression of canonical Wnt signaling. J Biol Chem 289:12168-76
Huang, Ping; Ho, Shiuh-Rong; Wang, Kai et al. (2011) Muscle-specific overexpression of NCOATGK, splice variant of O-GlcNAcase, induces skeletal muscle atrophy. Am J Physiol Cell Physiol 300:C456-65
Ho, Shiuh-Rong; Wang, Kai; Whisenhunt, Thomas R et al. (2010) O-GlcNAcylation enhances FOXO4 transcriptional regulation in response to stress. FEBS Lett 584:49-54
Wang, Kai; Ho, Shiuh-Rong; Mao, Weiming et al. (2009) Increased O-GlcNAc causes disrupted lens fiber cell differentiation and cataracts. Biochem Biophys Res Commun 387:70-6
Bowe, Damon B; Sadlonova, Andrea; Toleman, Clifford A et al. (2006) O-GlcNAc integrates the proteasome and transcriptome to regulate nuclear hormone receptors. Mol Cell Biol 26:8539-50
Whisenhunt, Thomas R; Yang, Xiaoyong; Bowe, Damon B et al. (2006) Disrupting the enzyme complex regulating O-GlcNAcylation blocks signaling and development. Glycobiology 16:551-63
Roh, Meejeon; Paterson, Andrew J; Liu, Kan et al. (2005) Proteolytic processing of TGFalpha redirects its mitogenic activity: the membrane-anchored form is autocrine, the secreted form is paracrine. Biochim Biophys Acta 1743:231-42
Roh, M; Paterson, A J; Asa, S L et al. (2001) Stage-sensitive blockade of pituitary somatomammotrope development by targeted expression of a dominant negative epidermal growth factor receptor in transgenic mice. Mol Endocrinol 15:600-13
Xie, W; Chow, L T; Paterson, A J et al. (1999) Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice. Oncogene 18:3593-607
Xie, W; Wu, X; Chow, L T et al. (1998) Targeted expression of activated erbB-2 to the epidermis of transgenic mice elicits striking developmental abnormalities in the epidermis and hair follicles. Cell Growth Differ 9:313-25

Showing the most recent 10 out of 29 publications