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Zeng, Fang-Mao; Liu, Ling-Yan; Zheng, Jin et al. (2016) Identification of a Fused-Ring 2'-Deoxyadenosine Adduct Formed in Human Cells Incubated with 1-Chloro-3-buten-2-one, a Potential Reactive Metabolite of 1,3-Butadiene. Chem Res Toxicol 29:1041-50
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Liu, Xin-Jie; Zeng, Fang-Mao; An, Jing et al. (2013) Cytotoxicity, genotoxicity, and mutagenicity of 1-chloro-2-hydroxy-3-butene and 1-chloro-3-buten-2-one, two alternative metabolites of 1,3-butadiene. Toxicol Appl Pharmacol 271:13-9
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Irving, Roy M; Elfarra, Adnan A (2013) Mutagenicity of the cysteine S-conjugate sulfoxides of trichloroethylene and tetrachloroethylene in the Ames test. Toxicology 306:157-61
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Sun, Liang; Pelah, Avishay; Zhang, Dong-Ping et al. (2013) Formation of fused-ring 2'-deoxycytidine adducts from 1-chloro-3-buten-2-one, an in vitro 1,3-butadiene metabolite, under in vitro physiological conditions. Chem Res Toxicol 26:1545-53
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Irving, Roy M; Pinkerton, Marie E; Elfarra, Adnan A (2013) Characterization of the chemical reactivity and nephrotoxicity of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine sulfoxide, a potential reactive metabolite of trichloroethylene. Toxicol Appl Pharmacol 267:1-10
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Elfarra, Adnan A; Zhang, Xin-Yu (2012) Alcohol dehydrogenase- and rat liver cytosol-dependent bioactivation of 1-chloro-2-hydroxy-3-butene to 1-chloro-3-buten-2-one, a bifunctional alkylating agent. Chem Res Toxicol 25:2600-7
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Irving, Roy M; Brownfield, Mark S; Elfarra, Adnan A (2011) N-biotinyl-S-(1,2-dichlorovinyl)-L-cysteine sulfoxide as a potential model for S-(1,2-dichlorovinyl)-L-cysteine sulfoxide: characterization of stability and reactivity with glutathione and kidney proteins in vitro. Chem Res Toxicol 24:1915-23
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Novick, Rachel M; Vezina, Chad M; Elfarra, Adnan A (2010) Isoform distinct time-, dose-, and castration-dependent alterations in flavin-containing monooxygenase expression in mouse liver after 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment. Biochem Pharmacol 79:1345-51
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Novick, Rachel M; Mitzey, Ann M; Brownfield, Mark S et al. (2009) Differential localization of flavin-containing monooxygenase (FMO) isoforms 1, 3, and 4 in rat liver and kidney and evidence for expression of FMO4 in mouse, rat, and human liver and kidney microsomes. J Pharmacol Exp Ther 329:1148-55
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Krause, Renee J; Elfarra, Adnan A (2009) Reduction of L-methionine selenoxide to seleno-L-methionine by endogenous thiols, ascorbic acid, or methimazole. Biochem Pharmacol 77:134-40
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Showing the most recent 10 out of 43 publications
