Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK044602-04
Application #
2143912
Study Section
Physiology Study Section (PHY)
Project Start
1992-09-30
Project End
1997-09-29
Budget Start
1995-09-30
Budget End
1997-09-29
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Physiology
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Zampighi, Guido A; Schietroma, Cataldo; Zampighi, Lorenzo M et al. (2011) Conical tomography of a ribbon synapse: structural evidence for vesicle fusion. PLoS One 6:e16944
Zampighi, Guido A; Fain, Nick; Zampighi, Lorenzo M et al. (2008) Conical electron tomography of a chemical synapse: polyhedral cages dock vesicles to the active zone. J Neurosci 28:4151-60
Faham, Salem; Watanabe, Akira; Besserer, Gabriel Mercado et al. (2008) The crystal structure of a sodium galactose transporter reveals mechanistic insights into Na+/sugar symport. Science 321:810-4
Voss, Andrew A; Diez-Sampedro, Ana; Hirayama, Bruce A et al. (2007) Imino sugars are potent agonists of the human glucose sensor SGLT3. Mol Pharmacol 71:628-34
Turk, Eric; Gasymov, Oktay K; Lanza, Seren et al. (2006) A reinvestigation of the secondary structure of functionally active vSGLT, the vibrio sodium/galactose cotransporter. Biochemistry 45:1470-9
Zampighi, G A; Zampighi, L M; Fain, N et al. (2006) Conical electron tomography of a chemical synapse: vesicles docked to the active zone are hemi-fused. Biophys J 91:2910-8
Lanzavecchia, S; Cantele, F; Bellon, P L et al. (2005) Conical tomography of freeze-fracture replicas: a method for the study of integral membrane proteins inserted in phospholipid bilayers. J Struct Biol 149:87-98
Zampighi, G A; Zampighi, L; Fain, N et al. (2005) Conical tomography II: A method for the study of cellular organelles in thin sections. J Struct Biol 151:263-74
Wright, Ernest M; Loo, Donald D F; Hirayama, Bruce A et al. (2004) Surprising versatility of Na+-glucose cotransporters: SLC5. Physiology (Bethesda) 19:370-6
Wright, Ernest M; Turk, Eric (2004) The sodium/glucose cotransport family SLC5. Pflugers Arch 447:510-8

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