Human Amino Acid Conjugation of Bile Acids

Barnes, Stephen

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK046390-03
• Application #: 2145591
• Study Section: General Medicine A Subcommittee 2 (GMA)
• Project Start: 1994-08-15
• Project End: 1999-01-31
• Budget Start: 1996-08-01
• Budget End: 1999-01-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Alabama Birmingham
• Department: Pharmacology
• Type: Schools of Dentistry
• DUNS #: 004514360
• City: Birmingham
• State: AL
• Country: United States
• Zip Code: 35294

Publications

Barnes, Stephen; Shonsey, Erin M; Eliuk, Shannon M et al. (2008) High-resolution mass spectrometry analysis of protein oxidations and resultant loss of function. Biochem Soc Trans 36:1037-44

Kang, Dae-Joong; Ridlon, Jason M; Moore 2nd, Doyle Ray et al. (2008) Clostridium scindens baiCD and baiH genes encode stereo-specific 7alpha/7beta-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductases. Biochim Biophys Acta 1781:16-25

Shonsey, E M; Eliuk, S M; Johnson, M S et al. (2008) Inactivation of human liver bile acid CoA:amino acid N-acyltransferase by the electrophilic lipid, 4-hydroxynonenal. J Lipid Res 49:282-94

Styles, Nathan A; Falany, Josie L; Barnes, Stephen et al. (2007) Quantification and regulation of the subcellular distribution of bile acid coenzyme A:amino acid N-acyltransferase activity in rat liver. J Lipid Res 48:1305-15

Shonsey, Erin M; Wheeler, James; Johnson, Michelle et al. (2005) Synthesis of bile acid coenzyme a thioesters in the amino acid conjugation of bile acids. Methods Enzymol 400:360-73

Shonsey, Erin M; Sfakianos, Mindan; Johnson, Michelle et al. (2005) Bile acid coenzyme A: amino acid N-acyltransferase in the amino acid conjugation of bile acids. Methods Enzymol 400:374-94

He, Dongning; Barnes, Stephen; Falany, Charles N (2003) Rat liver bile acid CoA:amino acid N-acyltransferase: expression, characterization, and peroxisomal localization. J Lipid Res 44:2242-9

Sfakianos, Mindan K; Wilson, Landon; Sakalian, Michael et al. (2002) Conserved residues in the putative catalytic triad of human bile acid Coenzyme A:amino acid N-acyltransferase. J Biol Chem 277:47270-5

Falany, Charles N; Xie, Xiaowei; Wheeler, James B et al. (2002) Molecular cloning and expression of rat liver bile acid CoA ligase. J Lipid Res 43:2062-71

King 3rd, L; Barnes, S; Glufke, U et al. (2000) The enzymatic formation of novel bile acid primary amides. Arch Biochem Biophys 374:107-17