Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK051281-01
Application #
2152381
Study Section
Endocrinology Study Section (END)
Project Start
1996-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Yuan, Chaoshen; Nguyen, Phuong; Baxter, John D et al. (2013) Distinct ligand-dependent and independent modes of thyroid hormone receptor (TR)/PGC-1? interaction. J Steroid Biochem Mol Biol 133:58-65
Yumoto, Fumiaki; Nguyen, Phuong; Sablin, Elena P et al. (2012) Structural basis of coactivation of liver receptor homolog-1 by ?-catenin. Proc Natl Acad Sci U S A 109:143-8
Cunha Lima, Suzana T; Rodrigues, Edson D (2011) The oligomeric state of thyroid receptor regulates hormone binding kinetics. J Endocrinol 210:125-34
Figueira, A C M; Saidemberg, D M; Souza, P C T et al. (2011) Analysis of agonist and antagonist effects on thyroid hormone receptor conformation by hydrogen/deuterium exchange. Mol Endocrinol 25:15-31
Martinez, Leandro; Nascimento, Alessandro S; Nunes, Fabio M et al. (2009) Gaining ligand selectivity in thyroid hormone receptors via entropy. Proc Natl Acad Sci U S A 106:20717-22
Cunha Lima, Suzana T; Nguyen, Ngoc-Ha; Togashi, Marie et al. (2009) Differential effects of TR ligands on hormone dissociation rates: evidence for multiple ligand entry/exit pathways. J Steroid Biochem Mol Biol 117:125-31
Jouravel, Natalia; Sablin, Elena; Togashi, Marie et al. (2009) Molecular basis for dimer formation of TRbeta variant D355R. Proteins 75:111-7
Govindan, Manjapra; Meng, Xianwang; Denis, Clyde L et al. (2009) Identification of CCR4 and other essential thyroid hormone receptor co-activators by modified yeast synthetic genetic array analysis. Proc Natl Acad Sci U S A 106:19854-9
Shah, Vanya; Nguyen, Phuong; Nguyen, Ngoc-Ha et al. (2008) Complex actions of thyroid hormone receptor antagonist NH-3 on gene promoters in different cell lines. Mol Cell Endocrinol 296:69-77
Estebanez-Perpina, Eva; Arnold, Leggy A; Arnold, Alexander A et al. (2007) A surface on the androgen receptor that allosterically regulates coactivator binding. Proc Natl Acad Sci U S A 104:16074-9

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