(taken from abstract) American hemodialysis patients are frequently malnourished. This contributes to dialysis patient mortality rates that are the highest in the industrialized world at 22% per year. Poor nutritional status probably also contributes to high health care costs (an average of two hospitalizations annually per patient and total Medicare expenditures of $11 billion per year) and diminished quality of life. Our prior work identified five potentially modifiable nutritional barriers (poor appetite, inadequate dialysis dose, poor nutritional knowledge, low fluid intake, and needing help shopping and cooking) and pilot tested a promising approach to overcome these barriers. This proposed community-based randomized controlled trial extends our prior work by targeting specific nutritional barriers with a tailored feedback and education intervention. Thirty dialysis facilities in northeast Ohio will be randomly assigned to intervention and control groups, with 135 malnourished patients enrolled from 15 intervention facilities and 135 from 15 control facilities. Baseline evaluation will include measures of nutritional status, specific barriers, inpatient expenditures, and quality of life. On a monthly basis for 12 months, intervention patients and their dietitians will receive tailored feedback and education on overcoming patient-specific barriers. They will then meet monthly to jointly formulate a care plan addressing these barriers. Control patients will continue to get usual care. Major analyses will compare changes in nutritional parameters, hospitalization-related costs, and quality of life in intervention vs. control patients with adjustment for nesting of patients within facilities. The proposed project will test a novel intervention that targets patients and providers as they together make nutrition-related decisions. Overcoming specific barriers may lead not only to improved nutritional status but also to better patient survival, decreased health care costs, and increased quality of life.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK051472-08
Application #
6369780
Study Section
Health Care Quality and Effectiveness Research (HQER)
Program Officer
Kusek, John W
Project Start
1996-02-20
Project End
2006-11-30
Budget Start
2002-03-15
Budget End
2003-02-28
Support Year
8
Fiscal Year
2002
Total Cost
$590,552
Indirect Cost
Name
Case Western Reserve University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Huml, Anne M; Sullivan, Catherine M; Pencak, Julie A et al. (2013) Accuracy of dialysis medical records in determining patients' interest in and suitability for transplantation. Clin Transplant 27:541-5
Sullivan, Catherine; Leon, Janeen B; Sayre, Srilekha S et al. (2012) Impact of navigators on completion of steps in the kidney transplant process: a randomized, controlled trial. Clin J Am Soc Nephrol 7:1639-45
Sullivan, Catherine; Sayre, Srilekha S; Leon, Janeen B et al. (2009) Effect of food additives on hyperphosphatemia among patients with end-stage renal disease: a randomized controlled trial. JAMA 301:629-35
Drawz, Paul E; Miller, R Tyler; Sehgal, Ashwini R (2008) Predicting hospital-acquired acute kidney injury--a case-controlled study. Ren Fail 30:848-55
Sehgal, Ashwini R; Sullivan, Catherine; Leon, Janeen B et al. (2008) Public health approach to addressing hyperphosphatemia among dialysis patients. J Ren Nutr 18:256-61
Sarathy, Srilekha; Sullivan, Catherine; Leon, Janeen B et al. (2008) Fast food, phosphorus-containing additives, and the renal diet. J Ren Nutr 18:466-70
Sullivan, Catherine M; Leon, Janeen B; Sehgal, Ashwini R (2007) Phosphorus-containing food additives and the accuracy of nutrient databases: implications for renal patients. J Ren Nutr 17:350-4
Butt, Saud; Leon, Janeen B; David, Carol L et al. (2007) The prevalence and nutritional implications of fast food consumption among patients receiving hemodialysis. J Ren Nutr 17:264-8
Leon, Janeen B; Albert, Jeffrey M; Gilchrist, Gina et al. (2006) Improving albumin levels among hemodialysis patients: a community-based randomized controlled trial. Am J Kidney Dis 48:28-36
Sullivan, Catherine; Leon, Janeen B; Sehgal, Ashwini R (2006) Job satisfaction among renal dietitians. J Ren Nutr 16:337-40

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