Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK053510-01
Application #
2462435
Study Section
Hematology Subcommittee 2 (HEM)
Program Officer
Badman, David G
Project Start
1998-02-01
Project End
1998-07-31
Budget Start
1998-02-01
Budget End
1998-07-31
Support Year
1
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Harju-Baker, Susanna; Costa, Flavia C; Fedosyuk, Halyna et al. (2008) Silencing of Agamma-globin gene expression during adult definitive erythropoiesis mediated by GATA-1-FOG-1-Mi2 complex binding at the -566 GATA site. Mol Cell Biol 28:3101-13
Fedosyuk, Halyna; Peterson, Kenneth R (2007) Deletion of the human beta-globin LCR 5'HS4 or 5'HS1 differentially affects beta-like globin gene expression in beta-YAC transgenic mice. Blood Cells Mol Dis 39:44-55
Harju, Susanna; Navas, Patrick A; Stamatoyannopoulos, George et al. (2005) Genome architecture of the human beta-globin locus affects developmental regulation of gene expression. Mol Cell Biol 25:8765-78
Blau, C Anthony; Barbas 3rd, Carlos F; Bomhoff, Anna L et al. (2005) {gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice. J Biol Chem 280:36642-7
Harju, Susanna; Fedosyuk, Halyna; Peterson, Kenneth R (2004) Rapid isolation of yeast genomic DNA: Bust n' Grab. BMC Biotechnol 4:8
Peterson, Kenneth R (2003) Transgenic mice carrying yeast artificial chromosomes. Expert Rev Mol Med 5:1-25
Peterson, Kenneth R (2003) Hemoglobin switching: new insights. Curr Opin Hematol 10:123-9
Li, Qiliang; Peterson, Kenneth R; Fang, Xiangdong et al. (2002) Locus control regions. Blood 100:3077-86
Harju, Susanna; McQueen, Kellie J; Peterson, Kenneth R (2002) Chromatin structure and control of beta-like globin gene switching. Exp Biol Med (Maywood) 227:683-700
Navas, P A; Peterson, K R; Li, Q et al. (2001) The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis. J Mol Biol 312:17-26

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