Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK063275-02
Application #
6693848
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Program Officer
Serrano, Jose
Project Start
2003-01-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$359,550
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02215
Moll, Herwig P; Lee, Andy; Peterson, Clayton R et al. (2016) A20 Haploinsufficiency Aggravates Transplant Arteriosclerosis in Mouse Vascular Allografts: Implications for Clinical Transplantation. Transplantation 100:e106-e116
Enesa, Karine; Moll, Herwig P; Luong, Le et al. (2015) A20 suppresses vascular inflammation by recruiting proinflammatory signaling molecules to intracellular aggresomes. FASEB J 29:1869-78
Studer, P; da Silva, C G; Revuelta Cervantes, J M et al. (2015) Significant lethality following liver resection in A20 heterozygous knockout mice uncovers a key role for A20 in liver regeneration. Cell Death Differ 22:2068-77
da Silva, Cleide Gonçalves; Cervantes, Jesus Revuelta; Studer, Peter et al. (2014) A20--an omnipotent protein in the liver: prometheus myth resolved? Adv Exp Med Biol 809:117-39
Mele, Alessandra; Cervantes, Jesus Revuelta; Chien, Victor et al. (2014) Single nucleotide polymorphisms at the TNFAIP3/A20 locus and susceptibility/resistance to inflammatory and autoimmune diseases. Adv Exp Med Biol 809:163-83
McGillicuddy, Fiona C; Moll, Herwig P; Farouk, Samira et al. (2014) Translational studies of A20 in atherosclerosis and cardiovascular disease. Adv Exp Med Biol 809:83-101
Moll, Herwig P; Lee, Andy; Minussi, Darlan C et al. (2014) A20 regulates atherogenic interferon (IFN)-? signaling in vascular cells by modulating basal IFN? levels. J Biol Chem 289:30912-24
da Silva, Cleide Gonçalves; Minussi, Darlan Conterno; Ferran, Christiane et al. (2014) A20 expressing tumors and anticancer drug resistance. Adv Exp Med Biol 809:65-81
Guedes, Renata Padilha; Csizmadia, Eva; Moll, Herwig P et al. (2014) A20 deficiency causes spontaneous neuroinflammation in mice. J Neuroinflammation 11:122
Arguello, Meztli; Paz, Suzanne; Ferran, Christiane et al. (2014) Anti-viral tetris: modulation of the innate anti-viral immune response by A20. Adv Exp Med Biol 809:49-64

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