NYU Langone Medical Center experienced an unprecedented storm on October 29th, 2012, causing damage that deeply impacted our patient care, research, and educational facilities. NYULMCs emergency power system was designed and built according to all safety codes to withstand a surge higher than the highest flood level for New York City in the past century. Superstorm Sandy obviously exceeded those levels. Although we safely evacuated over 300 patients from Tisch Hospital and Schwartz Health Care Center (HCC) in the midst of the storm, our main campus incurred extensive damage to its mechanical, electrical, and plumbing systems, requiring the temporary closure of our main campus. There are three basic science buildings, the Skirball Institute, the Smilow Research Center, and the Medical Science Building (MSB). The below-ground levels of two of these buildings, the Smilow Research Center and MSB, which included two vivarium facilities, were significantly damaged. The animal vivarium of Smilow was deemed completely unrecoverable. The MSB vivarium remains closed. While Skirball and Smilow were operational within two months post- Sandy, MSB remains closed and its phased reopening is expected to begin this summer. In addition, Bellevue Hospital, where the CTSI is located and where we conduct the evaluations that require skilled nursing assistance, was closed for over 3 months.

Public Health Relevance

Due to the rampant obesity epidemic; type 2 diabetes is also increasing at an alarming rate in the USA. Inaddition to the ill effects of diabetes on the eyes; kidneys; and limbs; there is now evidence that the brain isalso affected early in the disease. The goal of this research is to increase our understanding of how the brainis affected so as to be in a position to develop treatment strategies to try to protect the brain during diabetes.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
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Jones, Teresa L Z
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New York University
Schools of Medicine
New York
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Ardekani, Babak A; Convit, Antonio; Bachman, Alvin H (2016) Analysis of the MIRIAD Data Shows Sex Differences in Hippocampal Atrophy Progression. J Alzheimers Dis 50:847-57
Castro, Mary Grace; Venutolo, Christopher; Yau, Po Lai et al. (2016) Fitness, insulin sensitivity, and frontal lobe integrity in adults with overweight and obesity. Obesity (Silver Spring) 24:1283-9
Rusinek, Henry; Ha, Jenny; Yau, Po Lai et al. (2015) Cerebral perfusion in insulin resistance and type 2 diabetes. J Cereb Blood Flow Metab 35:95-102
Wang, Gene-Jack; Tomasi, Dardo; Convit, Antonio et al. (2014) BMI modulates calorie-dependent dopamine changes in accumbens from glucose intake. PLoS One 9:e101585
Yau, Po Lai; Kluger, Alan; Borod, Joan C et al. (2014) Neural substrates of verbal memory impairments in adults with type 2 diabetes mellitus. J Clin Exp Neuropsychol 36:74-87
Parasoglou, Prodromos; Xia, Ding; Chang, Gregory et al. (2013) Three-dimensional mapping of the creatine kinase enzyme reaction rate in muscles of the lower leg. NMR Biomed 26:1142-51
Hempel, R; Onopa, R; Convit, Antonio (2012) Type 2 diabetes affects hippocampus volume differentially in men and women. Diabetes Metab Res Rev 28:76-83
Yates, Kathy F; Sweat, Victoria; Yau, Po Lai et al. (2012) Impact of metabolic syndrome on cognition and brain: a selected review of the literature. Arterioscler Thromb Vasc Biol 32:2060-7
Convit, Antonio (2012) Obesity is associated with structural and functional brain abnormalities: where do we go from here? Psychosom Med 74:673-4
Duong, Michelle; Cohen, Jessica I; Convit, Antonio (2012) High cortisol levels are associated with low quality food choice in type 2 diabetes. Endocrine 41:76-81

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