240 young adolescents with Type 1 diabetes (DM1) will be studied in a three year prospective study that will include a comprehensive assessment of family and adolescent behavioral predictors and mediators of self- management, adherence to treatment, and DM1-related morbidity. The proposed study has the following specific aims: 1) to assess individual differences in patterns of self-management and adherence of DM1 from early to middle adolescence;2) identify family and adolescent behavioral influences on change in self- management and adherence;and 3) to document the consequences of self-management and adherence on blood sugar control, hyperglycemic episodes, and health care utilization. In order to accomplish these aims, a model of family and adolescent influences on self-management and adherence will be tested using data analytic methods that characterize individual trajectories of self-management over time. The following hypotheses will be tested: 1) quality of family communication and family support of diabetes management and autonomy will influence adolescents'behavioral autonomy and autonomy with respect to DM1 self- management and adherence;2) adolescents who demonstrate adaptive behavioral and diabetes-related autonomy and who are supported in their diabetes management by their parents will be more likely to develop effective, autonomous self-management and adherence;3) adaptive self-management and adherence to DM1 treatment will enhance blood sugar control, reduce frequency of hypoglycemia, and health care utilization. The proposed study will generate important, clinically relevant scientific data concerning the causes and consequences of self-management of DM1 diabetes during early adolescence. Information from the proposed study will facilitate the development of preventive interventions to address problem patterns of DM1 self-management among young adolescents in order to lessen the deterioration in DM1-related treatment adherence and glycemic control that often occurs during adolescence. The development of targeted interventions based on data from the proposed study will have public health significance for enhancement of blood sugar control and reduction of DM1 related morbidity in adolescents and young adults.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK069486-05
Application #
7898671
Study Section
Behavioral Medicine, Interventions and Outcomes Study Section (BMIO)
Program Officer
Hunter, Christine
Project Start
2006-08-01
Project End
2012-07-31
Budget Start
2010-08-01
Budget End
2012-07-31
Support Year
5
Fiscal Year
2010
Total Cost
$475,901
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Iskander, Jeannette M; Rohan, Jennifer M; Pendley, Jennifer Shroff et al. (2015) A 3-year prospective study of parent-child communication in early adolescents with type 1 diabetes: relationship to adherence and glycemic control. J Pediatr Psychol 40:109-20
Rohan, Jennifer M; Huang, Bin; Pendley, Jennifer Shroff et al. (2015) Predicting Health Resilience in Pediatric Type 1 Diabetes: A Test of the Resilience Model Framework. J Pediatr Psychol 40:956-67
Rohan, Jennifer M; Rausch, Joseph R; Pendley, Jennifer Shroff et al. (2014) Identification and prediction of group-based glycemic control trajectories during the transition to adolescence. Health Psychol 33:1143-52
Wu, Yelena P; Rausch, Joseph; Rohan, Jennifer M et al. (2014) Autonomy support and responsibility-sharing predict blood glucose monitoring frequency among youth with diabetes. Health Psychol 33:1224-31
Hilliard, Marisa E; Rohan, Jennifer M; Rausch, Joseph R et al. (2014) Patterns and predictors of paternal involvement in early adolescents' type 1 diabetes management over 3 years. J Pediatr Psychol 39:74-83
Ittenbach, Richard F; Cassedy, Amy E; Rohan, Jennifer M et al. (2013) Diabetes self-management profile short form: a preliminary report. J Clin Psychol Med Settings 20:107-13
Drotar, Dennis; Ittenbach, Richard; Rohan, Jennifer M et al. (2013) Diabetes management and glycemic control in youth with type 1 diabetes: test of a predictive model. J Behav Med 36:234-45
Miller, Megan M; Rohan, Jennifer M; Delamater, Alan et al. (2013) Changes in executive functioning and self-management in adolescents with type 1 diabetes: a growth curve analysis. J Pediatr Psychol 38:18-29
Rohan, Jennifer M; Pendley, Jennifer Shroff; Delamater, Alan et al. (2013) Patterns of self-management in pediatric type 1 diabetes predict level of glycemic control 2 years later. J Dev Behav Pediatr 34:186-96
Rausch, Joseph R; Hood, Korey K; Delamater, Alan et al. (2012) Changes in treatment adherence and glycemic control during the transition to adolescence in type 1 diabetes. Diabetes Care 35:1219-24

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