Pediatric diabetes looms as an emerging health care crisis in America. Both type 1 and 2 diabetes share common developmental issues that require successful adolescent/parent interactions to promote healthy self-care, particularly in diet and exercise behaviors. A Prevention Program to avoid adolescent self-care deterioration in T1D, the more virulent form, is proposed with a 3-site study that has a 23% minority representation. To facilitate maximum translation to routine clinical care, a brief, office-based treatment is planned (4, 30-min sessions) that will incorporate instruction in authoritative parenting, along with relevant coping skills of communication, problem solving, conflict resolution, and cognitive refraining. Treatment will be accompanied by comprehensive assessment to describe 1) correlates of self-care, including novel memory predictors, 2) moderators of treatment efficacy, and 3) innovative assessment of immediate response-to-treatment (RTT) behavioral trajectories. RTT will use data from 24-hour disease care interviews obtained during treatment inter-sessions for precise behavioral tracking of immediate session efficacy. We will map behavioral trajectories in response to treatment sessions to better understand what previously has been a 'black box'of year-long treatment. The proposed multi-site study with 3 locations should facilitate generalizability of results and the resultant large N of 190 should increase sensitivity to treatment effects. Powerful latent growth curve analyses and structural equation modeling will be utilized for data analysis, along with more traditional statistical techniques. A comprehensive biopsychosocial framework will be adopted that includes biological, psychological and sociofamial measurements of youths with diabetes and their parents. Approximately 190 11- to 14-year-olds will be assigned in a 5:1 proportion to either brief, office-based treatment or an attention control group. Previously, treatment groups have spanned wide age ranges such that the proposed narrow age range in the early adolescent years (11-14) should minimize broad developmental differences that may have obscured earlier results. Most subjects will be followed for up to 2 years'post-intervention. Better biometric outcomes (blood glucose levels, glycohemoglobin levels, fewer adverse events), along with better psychosocial outcomes (continued parental involvement in disease care, more frequent/better disease care), is predicted relative the attention control group.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK070917-03
Application #
7586061
Study Section
Behavioral Medicine, Interventions and Outcomes Study Section (BMIO)
Program Officer
Hunter, Christine
Project Start
2007-04-01
Project End
2012-03-31
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
3
Fiscal Year
2009
Total Cost
$602,076
Indirect Cost
Name
Virginia Commonwealth University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
105300446
City
Richmond
State
VA
Country
United States
Zip Code
23298
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Caccavale, Laura J; Weaver, Patrick; Chen, Rusan et al. (2015) Family Density and SES Related to Diabetes Management and Glycemic Control in Adolescents With Type 1 Diabetes. J Pediatr Psychol 40:500-8
Herbert, Linda Jones; Sweenie, Rachel; Kelly, Katherine Patterson et al. (2014) Using qualitative methods to evaluate a family behavioral intervention for type 1 diabetes. J Pediatr Health Care 28:376-85
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Hilliard, Marisa E; Holmes, Clarissa S; Chen, Rusan et al. (2013) Disentangling the roles of parental monitoring and family conflict in adolescents' management of type 1 diabetes. Health Psychol 32:388-96
Hendricks, Melissa; Monaghan, Maureen; Soutor, Sari et al. (2013) A profile of self-care behaviors in emerging adults with type 1 diabetes. Diabetes Educ 39:195-203
Herge, Whitney M; Streisand, Randi; Chen, Rusan et al. (2012) Family and youth factors associated with health beliefs and health outcomes in youth with type 1 diabetes. J Pediatr Psychol 37:980-9

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