This project is a competing continuation of our project entitled "Parallel Magnetic Resonance Imaging: New Techniques and Technologies," which yielded many of the seminal advances in highly accelerated parallel MRI, and demonstrated their use in imaging of the abdomen and the cardiovascular system. Our continuing project will apply these advances to the development and deployment of a rapid, simple, and comprehensive cardiac imaging protocol occupying a small number of breath-holds. We will also develop a novel goal-oriented user interface for rapid volumetric imaging, to reflect and extend the resulting simplification of workflow. Finally, we will develop the tools required to accomplish rapid volumetric cardiac imaging at high and ultrahigh field strength.

Public Health Relevance

This project is a competing continuation of our project entitled "Parallel Magnetic Resonance Imaging: New Techniques and Technologies," which produced many of the key advances in highly accelerated parallel MRI, and demonstrated their use in rapid imaging of the abdomen and the cardiovascular system. The focus of our continuing project will be to use parallel MRI to create a rapid and simple procedure for evaluating comprehensive cardiac heath in a mere few minutes. We will also develop the tools required to accomplish rapid cardiac imaging at high and ultrahigh field strength, where great diagnostic benefits are expected once key technological limitations have been addressed.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Research Project (R01)
Project #
5R01EB000447-10
Application #
8232947
Study Section
Medical Imaging Study Section (MEDI)
Program Officer
Liu, Guoying
Project Start
2002-04-15
Project End
2014-02-28
Budget Start
2012-03-01
Budget End
2014-02-28
Support Year
10
Fiscal Year
2012
Total Cost
$717,853
Indirect Cost
$289,680
Name
New York University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Ben-Eliezer, Noam; Sodickson, Daniel K; Block, Kai Tobias (2015) Rapid and accurate T2 mapping from multi-spin-echo data using Bloch-simulation-based reconstruction. Magn Reson Med 73:809-17
Otazo, Ricardo; Cand├Ęs, Emmanuel; Sodickson, Daniel K (2015) Low-rank plus sparse matrix decomposition for accelerated dynamic MRI with separation of background and dynamic components. Magn Reson Med 73:1125-36
Rosenkrantz, Andrew B; Geppert, Christian; Grimm, Robert et al. (2015) Dynamic contrast-enhanced MRI of the prostate with high spatiotemporal resolution using compressed sensing, parallel imaging, and continuous golden-angle radial sampling: preliminary experience. J Magn Reson Imaging 41:1365-73
Feng, Li; Grimm, Robert; Block, Kai Tobias et al. (2014) Golden-angle radial sparse parallel MRI: combination of compressed sensing, parallel imaging, and golden-angle radial sampling for fast and flexible dynamic volumetric MRI. Magn Reson Med 72:707-17
Chandarana, Hersh; Feng, Li; Block, Tobias K et al. (2013) Free-breathing contrast-enhanced multiphase MRI of the liver using a combination of compressed sensing, parallel imaging, and golden-angle radial sampling. Invest Radiol 48:10-6
Alon, Leeor; Deniz, Cem Murat; Brown, Ryan et al. (2013) Method for in situ characterization of radiofrequency heating in parallel transmit MRI. Magn Reson Med 69:1457-65
Deniz, Cem Murat; Brown, Ryan; Lattanzi, Riccardo et al. (2013) Maximum efficiency radiofrequency shimming: Theory and initial application for hip imaging at 7 tesla. Magn Reson Med 69:1379-88
Kim, Daniel; Dyvorne, Hadrien A; Otazo, Ricardo et al. (2012) Accelerated phase-contrast cine MRI using k-t SPARSE-SENSE. Magn Reson Med 67:1054-64
Deniz, Cem Murat; Alon, Leeor; Brown, Ryan et al. (2012) Specific absorption rate benefits of including measured electric field interactions in parallel excitation pulse design. Magn Reson Med 67:164-74
Zhu, Yudong; Alon, Leeor; Deniz, Cem M et al. (2012) System and SAR characterization in parallel RF transmission. Magn Reson Med 67:1367-78

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