Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES002638-15
Application #
2153168
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1981-07-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
15
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Kostial, K; Blanusa, M; Piasek, M et al. (1999) Combined chelation therapy in reducing tissue lead concentrations in suckling rats. J Appl Toxicol 19:143-7
Singh, P K; Jones, M M; Lane, J E et al. (1997) Synthesis and in vitro trypanocidal activity of some novel iron chelating agents. Arzneimittelforschung 47:311-5
Kostial, K; Restek-Samarzija, N; Blanusa, M et al. (1997) Combined oral treatment with racemic and meso-2,3-dimercaptosuccinic acid for removal of mercury in rats. Pharmacol Toxicol 81:242-4
Jones, M M; Xu, C; Ladd, P A (1997) Selenite suppression of cadmium-induced testicular apoptosis. Toxicology 116:169-75
Jones, M M; Singh, P K; Kostial, K et al. (1997) Comparative in vivo lead mobilization of meso- and rac-2,3-dimercaptosuccinic acids in albino Wistar rats. Pharmacol Toxicol 80:182-6
Yan, H; Carter, C E; Xu, C et al. (1997) Cadmium-induced apoptosis in the urogenital organs of the male rat and its suppression by chelation. J Toxicol Environ Health 52:149-68
Kostial, K; Restek-Samarzija, N; Blanusa, M et al. (1997) Racemic-2,3-dimercaptosuccinic acid for inorganic mercury mobilization in rats. J Appl Toxicol 17:71-4
Xu, C; Johnson, J E; Singh, P K et al. (1996) In vivo studies of cadmium-induced apoptosis in testicular tissue of the rat and its modulation by a chelating agent. Toxicology 107:1-8
Jones, M M; Xu, C; Singh, P K et al. (1996) Cadmium mobilization by nitrogen donor chelating agents. J Toxicol Environ Health 48:71-80
Jones, M M; Singh, P K; Lane, J E et al. (1996) Inhibition of Trypanosoma cruzi epimastigotes in vitro by iron chelating agents. Arzneimittelforschung 46:1158-62

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