Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES004362-08
Application #
2153672
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1987-08-01
Project End
1998-04-30
Budget Start
1995-05-01
Budget End
1998-04-30
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Purdue University
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907
Powley, M W; Carlson, G P (2000) Cytochromes P450 involved with benzene metabolism in hepatic and pulmonary microsomes. J Biochem Mol Toxicol 14:303-9
Powley, M W; Carlson, G P (1999) Species comparison of hepatic and pulmonary metabolism of benzene. Toxicology 139:207-17
Hynes, D E; DeNicola, D B; Carlson, G P (1999) Metabolism of styrene by mouse and rat isolated lung cells. Toxicol Sci 51:195-201
Felten, R K; DeNicola, D B; Carlson, G P (1998) Minimal effects of acrylonitrile on pulmonary and hepatic cell injury enzymes in rats with induced cytochrome P450. Drug Chem Toxicol 21:181-94
Carlson, G P; Hynes, D E; Mantick, N A (1998) Effects of inhibitors of CYP1A and CYP2B on styrene metabolism in mouse liver and lung microsomes. Toxicol Lett 98:131-7
Carlson, G P (1998) Metabolism of styrene oxide to styrene glycol by mouse liver and lung. J Toxicol Environ Health A 53:19-27
Carlson, G P (1997) Comparison of mouse strains for susceptibility to styrene-induced hepatotoxicity and pneumotoxicity. J Toxicol Environ Health 51:177-87
Carlson, G P (1997) Effects of inducers and inhibitors on the microsomal metabolism of styrene to styrene oxide in mice. J Toxicol Environ Health 51:477-88
Gadberry, M G; DeNicola, D B; Carlson, G P (1996) Pneumotoxicity and hepatotoxicity of styrene and styrene oxide. J Toxicol Environ Health 48:273-94
Carlson, G P (1996) Comparison of the effects of pyridine and its metabolites on rat liver and kidney. Toxicol Lett 85:173-8

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