Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES011344-09
Application #
6751324
Study Section
Chemical Pathology Study Section (CPA)
Program Officer
Reinlib, Leslie J
Project Start
2001-06-01
Project End
2006-05-31
Budget Start
2004-06-01
Budget End
2005-05-31
Support Year
9
Fiscal Year
2004
Total Cost
$312,000
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Pathology
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Singer, William D; Osimiri, Lindsey C; Friedberg, Errol C (2013) Increased dietary cholesterol promotes enhanced mutagenesis in DNA polymerase kappa-deficient mice. DNA Repair (Amst) 12:817-23
Guo, Caixia; Tang, Tie-Shan; Friedberg, Errol C (2010) SnapShot: nucleotide excision repair. Cell 140:754-4.e1
Stancel, J Nicole Kosarek; McDaniel, Lisa D; Velasco, Susana et al. (2009) Polk mutant mice have a spontaneous mutator phenotype. DNA Repair (Amst) 8:1355-62
Moore, Destaye M; Karlin, Justin; González-Barrera, Sergio et al. (2009) Rad10 exhibits lesion-dependent genetic requirements for recruitment to DNA double-strand breaks in Saccharomyces cerevisiae. Nucleic Acids Res 37:6429-38
Guo, Caixia; Kosarek-Stancel, J Nicole; Tang, Tie-Shan et al. (2009) Y-family DNA polymerases in mammalian cells. Cell Mol Life Sci 66:2363-81
Guo, Caixia; Tang, Tie-Shan; Bienko, Marzena et al. (2008) Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significance. J Biol Chem 283:4658-64
Kosarek, J Nicole; Woodruff, Rachel V; Rivera-Begeman, Amanda et al. (2008) Comparative analysis of in vivo interactions between Rev1 protein and other Y-family DNA polymerases in animals and yeasts. DNA Repair (Amst) 7:439-51
Guo, Caixia; Sonoda, Eiichiro; Tang, Tie-Shan et al. (2006) REV1 protein interacts with PCNA: significance of the REV1 BRCT domain in vitro and in vivo. Mol Cell 23:265-71
Guo, Caixia; Tang, Tie-Shan; Bienko, Marzena et al. (2006) Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damage. Mol Cell Biol 26:8892-900
Guo, Caixia; Fischhaber, Paula L; Luk-Paszyc, Margaret J et al. (2003) Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis. EMBO J 22:6621-30

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