Development of wearable sensors for point-of-contact, near-real time monitoring of exposure to environmental chemical species is critical to the success of studies of diverse populations. The demand for these sensors is driv- en by the yet unmet need for wearable sensors to simultaneously and selectively measure multiple analytes with negligible power consumption. In the proposed program, GE Global Research team will meet these require- ments for wearable sensors through the development of a new sensing platform that will dramatically decrease the complexity of accurate monitoring of airborne toxicants such as volatile organic compounds as well as re- ducing and oxidizing gases. The proposed sensor system will employ a novel sensing approach recently devel- oped at GE Global Research that utilizes resonant antenna structures of passive inductively coupled radio-fre- quency identification (RFID) sensors with organic electronic films that will serve as analyte-sensing coatings. This new sensing approach will provide selective quantitation of toxic volatile species with sub-ppm detection limits in presence of uncontrolled variations of ambient humidity. This response selectivity will be achieved not with an array of these sensors but with a single sensor. Such capability will be accomplished by capitalizing on (1) molecular recognition of gases by organic electronic polymers using several vapor-response mechanisms that act simultaneously, (2) new design of sensor transducer to fully probe these vapor-polymer interactions, and (3) standard multivariate analysis of the complex impedance response of the resonance sensor antenna structure. Developed sensors will be interrogated by a matchbox-sized, wearable sensor reader that will relate the findings to a local base station for a long-range transmission. The assembled research team has significant and recog- nized practical knowledge in chemical sensor design, synthesis of organic electronic polymers, low-power RF communications, and multivariate signal processing. This expertise will be coupled with key preliminary results that will facilitate the success of the proposed program.

Public Health Relevance

An unmet need for wearable sensors to simultaneously and selectively measure multiple analytes with negligible power consumption is a strong driving force in the development of new sensing concepts. In the proposed pro- gram, the team will employ a novel sensing approach that utilizes resonant antenna structures of passive induc- tively coupled radio-frequency identification (RFID) sensors with organic electronic films that will serve as ana- lyte-sensing coatings. This new sensing approach will provide a wearable, cost-effective, selective sensor for de- tection of toxic volatile species.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES016569-02
Application #
7925791
Study Section
Instrumentation and Systems Development Study Section (ISD)
Program Officer
Balshaw, David M
Project Start
2009-09-15
Project End
2011-07-31
Budget Start
2010-08-01
Budget End
2011-07-31
Support Year
2
Fiscal Year
2010
Total Cost
$943,338
Indirect Cost
Name
General Electric Global Research Center
Department
Type
DUNS #
086188401
City
Niskayuna
State
NY
Country
United States
Zip Code
12309
Potyrailo, Radislav A; Surman, Cheryl (2013) A Passive Radio-Frequency Identification (RFID) Gas Sensor With Self-Correction Against Fluctuations of Ambient Temperature. Sens Actuators B Chem 185:587-593
Potyrailo, Radislav A; Nagraj, Nandini; Surman, Cheryl et al. (2012) Wireless sensors and sensor networks for homeland security applications. Trends Analyt Chem 40:133-145
Potyrailo, Radislav A; Burns, Andrew; Surman, Cheryl et al. (2012) Multivariable passive RFID vapor sensors: roll-to-roll fabrication on a flexible substrate. Analyst 137:2777-81
Potyrailo, Radislav A; Nagraj, Nandini; Tang, Zhexiong et al. (2012) Battery-free radio frequency identification (RFID) sensors for food quality and safety. J Agric Food Chem 60:8535-43
Potyrailo, Radislav A; Surman, Cheryl; Nagraj, Nandini et al. (2011) Materials and transducers toward selective wireless gas sensing. Chem Rev 111:7315-54