We propose to assess the validity, usability, and value of a novel cell phone-based personal exposure measurement system known as "CalFit" in two existing epidemiologic studies. The CalFit system runs on commercially available Android phones, and as currently configured, we can collect data on physical activity with accelerometry, geographic location through a global positioning system (GPS), air pollution, and self- reported environments, including mood, and behaviors with ecological momentary assessment (EMA) through interactive text messages. The CalFit system has already undergone numerous controlled validation studies and is ready for evaluation in large epidemiological studies. The combined measurement of physical activity, location and mobility, exposure to air pollution, and EMA represents a major advance in sensor technology. We will evaluate the instrument in two ongoing epidemiological investigations: (1) the Healthy PLACES study in Southern California, which is examining the impact of the built environment on physical activity and obesity in a Smart Growth community and five adjacent communities;and (2) in the Transportation, Air Pollution and physical ActivitieS (TAPAS) project in Barcelona, Spain, focused on determinants of active commuting by bicycling or walking. Both studies have enrolled subjects and are actively collecting accelerometry, GPS, or travel survey data.
For Aim 1, we will validate the CalFit GPS and accelerometer by comparing the integrated sensor against current gold standard instruments (the Actigraph accelerometer and the Globalsat GPS).
In Aim 2, we will demonstrate the added value of the EMA texting system for understanding self-reported behavior, mood, and social and physical contexts as antecedents, concomitants, and consequences of environmental exposures.
For Aim 3, we will combine commercially available sensors with circuit boards developed by our team to measure nitrogen dioxide and ozone in the field. We will merge these data with GPS and accelerometry information to infer likely inhalations of air pollution. To demonstrate value added we will compare the inhalation estimates derived against those from assigning resolved spatial estimates of exposure to the home location. We will also deploy passive sensors for the two pollutants that yield an integrated 1-week sample. These will be compared with the real-time assessments to demonstrate the value added of having the locational and physical activity information merged with the real-time air pollution data, which will allow us to assess indoor and outdoor exposures, the likely inhalation, and the geographic context of the exposures. Cell phones are currently the most ubiquitous computing platform globally, and our research will demonstrate the viability of a cell phone as an exposure characterization tool that will have widespread utility for numerous epidemiological applications.

Public Health Relevance

Currently collection of individualized exposure data is intrusive to study participants and expensive, largely due to the need to wear multiple devices. Our research will integrate numerous data related to individual behaviors and environmental exposures using a cell phone. Because cell phones are already used extensively, our sensor offers substantial advantages for large epidemiological studies. Thus our research is highly relevant to the protection of public health because the new sensors will allow researchers to unobtrusively measure many environmental exposures in a way that is convenient to study subjects and relatively inexpensive to researchers.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
3R01ES020409-02S1
Application #
8619721
Study Section
Special Emphasis Panel (ZES1-SET-D (RV))
Program Officer
Balshaw, David M
Project Start
2011-09-15
Project End
2014-08-31
Budget Start
2013-02-21
Budget End
2014-08-31
Support Year
2
Fiscal Year
2013
Total Cost
$99,611
Indirect Cost
$18,440
Name
University of California Berkeley
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
124726725
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Dunton, Genevieve Fridlund; Almanza, Estela; Jerrett, Michael et al. (2014) Neighborhood park use by children: use of accelerometry and global positioning systems. Am J Prev Med 46:136-42
Donaire-Gonzalez, David; de Nazelle, Audrey; Seto, Edmund et al. (2013) Comparison of physical activity measures using mobile phone-based CalFit and Actigraph. J Med Internet Res 15:e111
de Nazelle, Audrey; Seto, Edmund; Donaire-Gonzalez, David et al. (2013) Improving estimates of air pollution exposure through ubiquitous sensing technologies. Environ Pollut 176:92-9
Jerrett, Michael; Almanza, Estela; Davies, Molly et al. (2013) Smart growth community design and physical activity in children. Am J Prev Med 45:386-92