Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY001959-20
Application #
2158294
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1977-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wright State University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Dayton
State
OH
Country
United States
Zip Code
45435
Organisciak, Daniel; Darrow, Ruth; Barsalou, Linda et al. (2011) Light induced and circadian effects on retinal photoreceptor cell crystallins. Photochem Photobiol 87:151-9
Organisciak, Daniel T; Vaughan, Dana K (2010) Retinal light damage: mechanisms and protection. Prog Retin Eye Res 29:113-34
Marc, Robert E; Jones, B W; Watt, C B et al. (2008) Extreme retinal remodeling triggered by light damage: implications for age related macular degeneration. Mol Vis 14:782-806
Organisciak, Daniel; Darrow, Ruth; Gu, Xiaorong et al. (2006) Genetic, age and light mediated effects on crystallin protein expression in the retina. Photochem Photobiol 82:1088-96
Duncan, Todd; Wiggert, Barbara; Whittaker, Noel et al. (2006) Effect of visible light on normal and P23H-3 transgenic rat retinas: characterization of a novel retinoic acid derivative present in the P23H-3 retina. Photochem Photobiol 82:741-5
Grewal, Ruby; Organisciak, Daniel; Wong, Paul (2006) Factors underlying circadian dependent susceptibility to light induced retinal damage. Adv Exp Med Biol 572:411-6
Palamalai, Vikram; Darrow, Ruth M; Organisciak, Daniel T et al. (2006) Light-induced changes in protein nitration in photoreceptor rod outer segments. Mol Vis 12:1543-51
Sun, Mingjiang; Finnemann, Silvia C; Febbraio, Maria et al. (2006) Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions. J Biol Chem 281:4222-30
Ablonczy, Z; Darrow, R M; Knapp, D R et al. (2005) Rhodopsin phosphorylation in rats exposed to intense light. Photochem Photobiol 81:541-7
Grewal, Ruby; Stepczynski, Jadwiga; Kelln, Rhonda et al. (2004) Coordinated changes in classes of ribosomal protein gene expression is associated with light-induced retinal degeneration. Invest Ophthalmol Vis Sci 45:3885-95

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