Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
2R01EY002120-19A1
Application #
2158352
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1977-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Pitha, Ian; Oglesby, Ericka; Chow, Amanda et al. (2018) Rho-Kinase Inhibition Reduces Myofibroblast Differentiation and Proliferation of Scleral Fibroblasts Induced by Transforming Growth Factor ? and Experimental Glaucoma. Transl Vis Sci Technol 7:6
Kimball, Elizabeth C; Jefferys, Joan L; Pease, Mary E et al. (2018) The effects of age on mitochondria, axonal transport, and axonal degeneration after chronic IOP elevation using a murine ocular explant model. Exp Eye Res 172:78-85
Levin, Leonard A; Crowe, Megan E; Quigley, Harry A et al. (2017) Neuroprotection for glaucoma: Requirements for clinical translation. Exp Eye Res 157:34-37
Kimball, Elizabeth C; Pease, Mary E; Steinhart, Matthew R et al. (2017) A mouse ocular explant model that enables the study of living optic nerve head events after acute and chronic intraocular pressure elevation: Focusing on retinal ganglion cell axons and mitochondria. Exp Eye Res 160:106-115
Midgett, Dan E; Pease, Mary E; Jefferys, Joan L et al. (2017) The pressure-induced deformation response of the human lamina cribrosa: Analysis of regional variations. Acta Biomater 53:123-139
Nguyen, Cathy; Midgett, Dan; Kimball, Elizabeth C et al. (2017) Measuring Deformation in the Mouse Optic Nerve Head and Peripapillary Sclera. Invest Ophthalmol Vis Sci 58:721-733
Fu, Jie; Sun, Fengying; Liu, Wenhua et al. (2016) Subconjunctival Delivery of Dorzolamide-Loaded Poly(ether-anhydride) Microparticles Produces Sustained Lowering of Intraocular Pressure in Rabbits. Mol Pharm 13:2987-95
Oglesby, Ericka N; Tezel, Gülgün; Cone-Kimball, Elizabeth et al. (2016) Scleral fibroblast response to experimental glaucoma in mice. Mol Vis 22:82-99
Murienne, Barbara J; Jefferys, Joan L; Quigley, Harry A et al. (2015) The effects of glycosaminoglycan degradation on the mechanical behavior of the posterior porcine sclera. Acta Biomater 12:195-206
Pijanka, Jacek K; Spang, Martin T; Sorensen, Thomas et al. (2015) Depth-dependent changes in collagen organization in the human peripapillary sclera. PLoS One 10:e0118648

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