Abstract

The objectives of this grant renewal application are clinical and basic on the clinical level (1) is to clarify the interaction of the many factors involved in the production and severity of acute and cicatricial retrolental fibroplasia (RLF) in the premature population by multiple logistic risk analysis, (2) to investigate in selected """"""""high risk"""""""" prematures the role of arterial oxygen tension in the genesis of acute, proliferative RLF, and (3) on the more basic level, to explore a promising animal model for the production of cicatricial RLF.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY003513-05
Application #
3257845
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1981-06-08
Project End
1986-05-31
Budget Start
1985-06-01
Budget End
1986-05-31
Support Year
5
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
University of Miami School of Medicine
Department
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33101

  Publications

Flynn, J T; Bancalari, E; Snyder, E S et al. (1992) A cohort study of transcutaneous oxygen tension and the incidence and severity of retinopathy of prematurity. N Engl J Med 326:1050-4
Flynn, J T; Bancalari, E; Snyder, E S et al. (1991) A cohort study of transcutaneous oxygen tension and the incidence and severity of retinopathy of prematurity. Trans Am Ophthalmol Soc 89:77-92;discussion 92-5
Flynn, J T (1988) An International Classification of Retinopathy of Prematurity: development of the classification of the late stages of retinopathy of prematurity. Birth Defects Orig Artic Ser 24:175-83, C2-3
Bandstra, E S; Montalvo, B M; Goldberg, R N et al. (1988) Prophylactic indomethacin for prevention of intraventricular hemorrhage in premature infants. Pediatrics 82:533-42
Flynn, J T; Bancalari, E; Bachynski, B N et al. (1987) Retinopathy of prematurity. Diagnosis, severity, and natural history. Ophthalmology 94:620-9
(1987) An international classification of retinopathy of prematurity. II. The classification of retinal detachment. The International Committee for the Classification of the Late Stages of Retinopathy of Prematurity. Arch Ophthalmol 105:906-12
Flynn, J T; Bancalari, E; Bawol, R et al. (1987) Retinopathy of prematurity. A randomized, prospective trial of transcutaneous oxygen monitoring. Ophthalmology 94:630-8
Flynn, J T (1987) Retinopathy of prematurity. Pediatr Clin North Am 34:1487-516
Bancalari, E; Flynn, J; Goldberg, R N et al. (1987) Influence of transcutaneous oxygen monitoring on the incidence of retinopathy of prematurity. Pediatrics 79:663-9
Flynn, J T (1986) Retrolental fibroplasia: update. Trans New Orleans Acad Ophthalmol 34:293-325

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