Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY005758-07
Application #
3261225
Study Section
Pathology B Study Section (PTHB)
Project Start
1985-04-01
Project End
1991-06-30
Budget Start
1991-03-01
Budget End
1991-06-30
Support Year
7
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Chen, Yumay; Riley, Daniel J; Zheng, Lei et al. (2002) Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation. J Biol Chem 277:49408-16
Shan, B; Chang, C Y; Jones, D et al. (1994) The transcription factor E2F-1 mediates the autoregulation of RB gene expression. Mol Cell Biol 14:299-309
Shan, B; Lee, W H (1994) Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol Cell Biol 14:8166-73
Durfee, T; Mancini, M A; Jones, D et al. (1994) The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing. J Cell Biol 127:609-22
Riley, D J; Lai, C C; Chang, C Y et al. (1994) Susceptibility to tumors induced in mice by ethylnitrosourea is independent of retinoblastoma gene dosage. Cancer Res 54:6097-101
Hensey, C E; Hong, F; Durfee, T et al. (1994) Identification of discrete structural domains in the retinoblastoma protein. Amino-terminal domain is required for its oligomerization. J Biol Chem 269:1380-7
Hollingsworth Jr, R E; Hensey, C E; Lee, W H (1993) Retinoblastoma protein and the cell cycle. Curr Opin Genet Dev 3:55-62
Shan, B; Zhu, X; Chen, P L et al. (1992) Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F. Mol Cell Biol 12:5620-31
Chen, P L; Chen, Y; Shan, B et al. (1992) Stability of retinoblastoma gene expression determines the tumorigenicity of reconstituted retinoblastoma cells. Cell Growth Differ 3:119-25
Lee, E Y; Huang, S; Shew, J Y et al. (1991) Diverse mutations lead to inactivation of the retinoblastoma gene. Prog Clin Biol Res 362:221-40

Showing the most recent 10 out of 28 publications