Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY006513-10
Application #
2160376
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1987-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
New York Medical College
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Valhalla
State
NY
Country
United States
Zip Code
10595
Bellner, Lars; Marrazzo, Giuseppina; van Rooijen, Nico et al. (2015) Heme oxygenase-2 deletion impairs macrophage function: implication in wound healing. FASEB J 29:105-15
Fox, Timothy; Gotlinger, Katherine H; Dunn, Michael W et al. (2013) Dysregulated heme oxygenase-ferritin system in pterygium pathogenesis. Cornea 32:1276-82
Bellner, Lars; Wolstein, Jesse; Patil, Kiran A et al. (2011) Biliverdin Rescues the HO-2 Null Mouse Phenotype of Unresolved Chronic Inflammation Following Corneal Epithelial Injury. Invest Ophthalmol Vis Sci 52:3246-53
Marrazzo, Giuseppina; Bellner, Lars; Halilovic, Adna et al. (2011) The role of neutrophils in corneal wound healing in HO-2 null mice. PLoS One 6:e21180
Halilovic, Adna; Patil, Kiran A; Bellner, Lars et al. (2011) Knockdown of heme oxygenase-2 impairs corneal epithelial cell wound healing. J Cell Physiol 226:1732-40
Bellner, Lars; Patil, Kiran A; Castellano, Kirkland et al. (2011) Targeted suppression of HO-2 gene expression impairs the innate anti-inflammatory and repair responses of the cornea to injury. Mol Vis 17:1144-52
Schwartzman, Michal Laniado; Iserovich, Pavel; Gotlinger, Katherine et al. (2010) Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy. Diabetes 59:1780-8
Bellner, Lars; Martinelli, Lucia; Halilovic, Adna et al. (2009) Heme oxygenase-2 deletion causes endothelial cell activation marked by oxidative stress, inflammation, and angiogenesis. J Pharmacol Exp Ther 331:925-32
Patil, Kiran; Bellner, Lars; Cullaro, Giuseppe et al. (2008) Heme oxygenase-1 induction attenuates corneal inflammation and accelerates wound healing after epithelial injury. Invest Ophthalmol Vis Sci 49:3379-86
Bellner, Lars; Vitto, Marco; Patil, Kiran A et al. (2008) Exacerbated corneal inflammation and neovascularization in the HO-2 null mice is ameliorated by biliverdin. Exp Eye Res 87:268-78

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