Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY007042-10
Application #
2161212
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1986-09-30
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Pharmacology
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Orme, Mariam H; Liccardi, Gianmaria; Moderau, Nina et al. (2016) The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles. Nat Commun 7:10972
Hazim, Roni; Jiang, Mei; Esteve-Rudd, Julian et al. (2016) Live-Cell Imaging of Phagosome Motility in Primary Mouse RPE Cells. Adv Exp Med Biol 854:751-5
Frost, Laura S; Lopes, Vanda S; Bragin, Alvina et al. (2015) The Contribution of Melanoregulin to Microtubule-Associated Protein 1 Light Chain 3 (LC3) Associated Phagocytosis in Retinal Pigment Epithelium. Mol Neurobiol 52:1135-1151
Volland, Stefanie; Esteve-Rudd, Julian; Hoo, Juyea et al. (2015) A comparison of some organizational characteristics of the mouse central retina and the human macula. PLoS One 10:e0125631
Strong, Randy; Miller, Richard A; Astle, Clinton M et al. (2013) Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci 68:6-16
Ashraf, Shazia; Gee, Heon Yung; Woerner, Stephanie et al. (2013) ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption. J Clin Invest 123:5179-89
Frost, Laura S; Lopes, Vanda S; Stefano, Frank P et al. (2013) Loss of melanoregulin (MREG) enhances cathepsin-D secretion by the retinal pigment epithelium. Vis Neurosci 30:55-64
Lopes, V S; Boye, S E; Louie, C M et al. (2013) Retinal gene therapy with a large MYO7A cDNA using adeno-associated virus. Gene Ther 20:824-33
Da Cruz, Sandrine; Parone, Philippe A; Lopes, Vanda S et al. (2012) Elevated PGC-1? activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS. Cell Metab 15:778-86
Harkewicz, Richard; Du, Hongjun; Tong, Zongzhong et al. (2012) Essential role of ELOVL4 protein in very long chain fatty acid synthesis and retinal function. J Biol Chem 287:11469-80

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