Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY007864-07
Application #
2161742
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1989-08-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Florida
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Li, Qiuhong; Timmers, Adrian M; Guy, John et al. (2008) Cone-specific expression using a human red opsin promoter in recombinant AAV. Vision Res 48:332-8
Kwon, Brian K; Liu, Jie; Lam, Clarrie et al. (2007) Brain-derived neurotrophic factor gene transfer with adeno-associated viral and lentiviral vectors prevents rubrospinal neuronal atrophy and stimulates regeneration-associated gene expression after acute cervical spinal cord injury. Spine (Phila Pa 1976) 32:1164-73
Glushakova, Lyudmyla G; Timmers, Adrian M; Issa, Tawfik M et al. (2006) Does recombinant adeno-associated virus-vectored proximal region of mouse rhodopsin promoter support only rod-type specific expression in vivo? Mol Vis 12:298-309
Nusinowitz, S; Ridder 3rd, W H; Pang, J J et al. (2006) Cortical visual function in the rd12 mouse model of Leber Congenital Amarousis (LCA) after gene replacement therapy to restore retinal function. Vision Res 46:3926-34
Glushakova, Lyudmyla G; Timmers, Adrian M; Pang, Jijing et al. (2006) Human blue-opsin promoter preferentially targets reporter gene expression to rat s-cone photoreceptors. Invest Ophthalmol Vis Sci 47:3505-13
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Guy, J; Qi, X; Wang, H et al. (1999) Adenoviral gene therapy with catalase suppresses experimental optic neuritis. Arch Ophthalmol 117:1533-9
Guy, J; Qi, X; Hauswirth, W W (1998) Adeno-associated viral-mediated catalase expression suppresses optic neuritis in experimental allergic encephalomyelitis. Proc Natl Acad Sci U S A 95:13847-52
Yan, W; Lewin, A; Hauswirth, W (1998) Selective degradation of nonsense beta-phosphodiesterase mRNA in the heterozygous rd mouse. Invest Ophthalmol Vis Sci 39:2529-36
Flannery, J G; Zolotukhin, S; Vaquero, M I et al. (1997) Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus. Proc Natl Acad Sci U S A 94:6916-21

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