Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY008343-07
Application #
2162197
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1990-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Physiology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
McLaughlin, Charles W; Zellhuber-McMillan, Sylvia; Macknight, Anthony D C et al. (2007) Electron microprobe analysis of rabbit ciliary epithelium indicates enhanced secretion posteriorly and enhanced absorption anteriorly. Am J Physiol Cell Physiol 293:C1455-66
Do, C W; Civan, M M (2006) Swelling-activated chloride channels in aqueous humour formation: on the one side and the other. Acta Physiol (Oxf) 187:345-52
Do, Chi Wai; Peterson-Yantorno, Kim; Civan, Mortimer M (2006) Swelling-activated Cl- channels support Cl- secretion by bovine ciliary epithelium. Invest Ophthalmol Vis Sci 47:2576-82
Yang, Hui; Avila, Marcel Y; Peterson-Yantorno, Kim et al. (2005) The cross-species A3 adenosine-receptor antagonist MRS 1292 inhibits adenosine-triggered human nonpigmented ciliary epithelial cell fluid release and reduces mouse intraocular pressure. Curr Eye Res 30:747-54
Do, Chi Wai; Lu, Wennan; Mitchell, Claire H et al. (2005) Inhibition of swelling-activated Cl- currents by functional anti-ClC-3 antibody in native bovine non-pigmented ciliary epithelial cells. Invest Ophthalmol Vis Sci 46:948-55
Do, Chi-Wai; Peterson-Yantorno, Kim; Mitchell, Claire H et al. (2004) cAMP-activated maxi-Cl(-) channels in native bovine pigmented ciliary epithelial cells. Am J Physiol Cell Physiol 287:C1003-11
Civan, Mortimer M; Macknight, Anthony D C (2004) The ins and outs of aqueous humour secretion. Exp Eye Res 78:625-31
Do, C W; Civan, M M (2004) Basis of chloride transport in ciliary epithelium. J Membr Biol 200:1-13
McLaughlin, Charles W; Zellhuber-McMillan, Sylvia; Macknight, Anthony D C et al. (2004) Electron microprobe analysis of ouabain-exposed ciliary epithelium: PE-NPE cell couplets form the functional units. Am J Physiol Cell Physiol 286:C1376-89
Civan, Mortimer M (2003) Foreword to symposium ""forty years of epithelial transport-specificity and commonality"": a tribute to Professor Jose A Zadunaisky. J Exp Zool A Comp Exp Biol 300:3-4

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