Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
3R01EY008566-01A1S1
Application #
3265938
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1991-02-01
Project End
1995-01-31
Budget Start
1991-02-01
Budget End
1992-01-31
Support Year
1
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Scrofano, M M; Jahngen-Hodge, J; Nowell Jr, T R et al. (1998) The effects of aging and calorie restriction on plasma nutrient levels in male and female Emory mice. Mech Ageing Dev 105:31-44
Scrofano, M M; Shang, F; Nowell Jr, T R et al. (1998) Calorie restriction, stress and the ubiquitin-dependent pathway in mouse livers. Mech Ageing Dev 105:273-90
Scrofano, M M; Shang, F; Nowell Jr, T R et al. (1998) Aging, calorie restriction and ubiquitin-dependent proteolysis in the livers of Emory mice. Mech Ageing Dev 101:277-96
Taylor, A; Nowell, T (1997) Oxidative stress and antioxidant function in relation to risk for cataract. Adv Pharmacol 38:515-36
Taylor, A; Jacques, P F; Nowell, T et al. (1997) Vitamin C in human and guinea pig aqueous, lens and plasma in relation to intake. Curr Eye Res 16:857-64
Gong, X; Shang, F; Obin, M et al. (1997) Antioxidant enzyme activities in lens, liver and kidney of calorie restricted Emory mice. Mech Ageing Dev 99:181-92
Shang, F; Gong, X; Palmer, H J et al. (1997) Age-related decline in ubiquitin conjugation in response to oxidative stress in the lens. Exp Eye Res 64:21-30
Shang, F; Taylor, A (1995) Oxidative stress and recovery from oxidative stress are associated with altered ubiquitin conjugating and proteolytic activities in bovine lens epithelial cells. Biochem J 307 ( Pt 1):297-303
Taylor, A; Jacques, P F; Epstein, E M (1995) Relations among aging, antioxidant status, and cataract. Am J Clin Nutr 62:1439S-1447S
Shang, F; Huang, L; Taylor, A (1994) Degradation of native and oxidized beta- and gamma-crystallin using bovine lens epithelial cell and rabbit reticulocyte extracts. Curr Eye Res 13:423-31

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