Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
2R01EY009392-04A1
Application #
2163016
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1992-01-01
Project End
1998-12-31
Budget Start
1996-01-30
Budget End
1996-12-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cedars-Sinai Medical Center
Department
Type
DUNS #
075307785
City
Los Angeles
State
CA
Country
United States
Zip Code
90048
Dasgupta, Gargi; Nesburn, Anthony B; Wechsler, Steven L et al. (2010) Developing an asymptomatic mucosal herpes vaccine: the present and the future. Future Microbiol 5:1-4
Dasgupta, Gargi; Chentoufi, Aziz A; Nesburn, Anthony B et al. (2009) New concepts in herpes simplex virus vaccine development: notes from the battlefield. Expert Rev Vaccines 8:1023-35
Nesburn, Anthony B; Ramos, Thomas V; Zhu, Xiaoming et al. (2005) Local and systemic B cell and Th1 responses induced following ocular mucosal delivery of multiple epitopes of herpes simplex virus type 1 glycoprotein D together with cytosine-phosphate-guanine adjuvant. Vaccine 23:873-83
BenMohamed, Lbachir; Bertrand, Georges; McNamara, Cory D et al. (2003) Identification of novel immunodominant CD4+ Th1-type T-cell peptide epitopes from herpes simplex virus glycoprotein D that confer protective immunity. J Virol 77:9463-73
BenMohamed, Lbachir; Wechsler, Steven L; Nesburn, Anthony B (2002) Lipopeptide vaccines--yesterday, today, and tomorrow. Lancet Infect Dis 2:425-31
Nesburn, A B; Burke, R L; Ghiasi, H et al. (1998) A therapeutic vaccine that reduces recurrent herpes simplex virus type 1 corneal disease. Invest Ophthalmol Vis Sci 39:1163-70
Nesburn, A B; Slanina, S; Burke, R L et al. (1998) Local periocular vaccination protects against eye disease more effectively than systemic vaccination following primary ocular herpes simplex virus infection in rabbits. J Virol 72:7715-21
Nesburn, A B; Burke, R L; Ghiasi, H et al. (1998) Therapeutic periocular vaccination with a subunit vaccine induces higher levels of herpes simplex virus-specific tear secretory immunoglobulin A than systemic vaccination and provides protection against recurrent spontaneous ocular shedding of virus in la Virology 252:200-9
Nesburn, A B; Burke, R L; Ghiasi, H et al. (1994) Vaccine therapy for ocular herpes simplex virus (HSV) infection: periocular vaccination reduces spontaneous ocular HSV type 1 shedding in latently infected rabbits. J Virol 68:5084-92
Ghiasi, H; Kaiwar, R; Nesburn, A B et al. (1992) Baculovirus-expressed glycoprotein G of herpes simplex virus type 1 partially protects vaccinated mice against lethal HSV-1 challenge. Virology 190:233-9

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