The US population is aging dramatically. Vision changes are virtually inevitable with increasing age. Loss of vision is a major obstacle to independent living which reduces the quality of life in old age. The initial phase of this project has extended our knowledge about vision function among the elderly and its relationship to vision task performance, subjective visual complaints and general health and functioning. Data on a wide array of vision functions have been gathered on 902 randomly selected, community-living participants over the age of 55 including an unusually large number, nearly 300, over 80 years, a subgroup whose vision function was essentially unknown. Many important goals of aging studies can now be addressed by the proposed longitudinal study for which the established study cohort, validated vision tests and concurrent epidemiologic study of health and functioning present a unique opportunity. The cohort will be tested twice more during the study period using the vision test battery, questionnaires (including the NEI Quality of Life instrument), and visual task performance measures. Driving and medical records will also be collected. An independently funded, longitudinal research program will be continued to evaluate general health, nutrition and physical functioning. This information in combination with the vision-related results will provide a data set unique in scope. Specific goals include characterization of the changes in vision function and visual task performance with age; determination of health, nutrition and other risk factors for loss of vision function; assessment of the ability of the vision measures to prospectively predict health status; and development of combined risk factor models to explain the synergistic interactions between vision and other health/functioning deficits in affecting everyday task performance and quality of life. The existing collaboration between Smith-Kettlewell Eye Research Institute and the epidemiological research program at the Buck Center for Research in Aging is a unique opportunity to address issues of broad scope and importance that would otherwise require enormous financial and human resources. At the same time, valuable data on vision changes with age will be made available on a population of rapidly increasing importance whose vision function has never before been comprehensively studied.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY009588-08
Application #
6350859
Study Section
Special Emphasis Panel (ZRG1-VISB (02))
Program Officer
Oberdorfer, Michael
Project Start
1993-07-01
Project End
2003-01-31
Budget Start
2001-02-01
Budget End
2002-01-31
Support Year
8
Fiscal Year
2001
Total Cost
$461,577
Indirect Cost
Name
Smith-Kettlewell Eye Research Institute
Department
Type
DUNS #
City
San Francisco
State
CA
Country
United States
Zip Code
94115
Schneck, Marilyn E; Haegerstrom-Portnoy, Gunilla; Lott, Lori A et al. (2014) Comparison of panel D-15 tests in a large older population. Optom Vis Sci 91:284-90
Haegerstrom-Portnoy, Gunilla; Schneck, Marilyn E; Lott, Lori A et al. (2014) Longitudinal increase in anisometropia in older adults. Optom Vis Sci 91:60-7
Lott, Lori A; Schneck, Marilyn E; Haegerström-Portnoy, Gunilla et al. (2010) Non-standard vision measures predict mortality in elders: the Smith-Kettlewell Institute (SKI) study. Ophthalmic Epidemiol 17:242-50
Schneck, Marilyn E; Haegerstom-Portnoy, Gunilla; Lott, Lori A et al. (2010) Monocular vs. binocular measurement of spatial vision in elders. Optom Vis Sci 87:526-31
Haegerstrom-Portnoy, Gunilla (2005) The Glenn A. Fry Award Lecture 2003: Vision in elders--summary of findings of the SKI study. Optom Vis Sci 82:87-93
Lott, Lori A; Haegerstrom-Portnoy, Gunilla; Schneck, Marilyn E et al. (2005) Face recognition in the elderly. Optom Vis Sci 82:874-81
Brabyn, John A; Schneck, Marilyn E; Lott, Lori A et al. (2005) Night driving self-restriction: vision function and gender differences. Optom Vis Sci 82:755-64
Schneck, Marilyn E; Haegerstrom-Portnoy, Gunilla; Lott, Lori A et al. (2004) Low contrast vision function predicts subsequent acuity loss in an aged population: the SKI study. Vision Res 44:2317-25
West, Catherine G; Gildengorin, Ginny; Haegerstrom-Portnoy, Gunilla et al. (2003) Vision and driving self-restriction in older adults. J Am Geriatr Soc 51:1348-55
Schneck, Marilyn E; Haegerstrom-Portnoy, Gunilla (2003) Practical assessment of vision in the elderly. Ophthalmol Clin North Am 16:269-87

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