Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY011105-02
Application #
2165377
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1995-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Tummala, Shanti R; Dhingra, Anuradha; Fina, Marie E et al. (2016) Lack of mGluR6-related cascade elements leads to retrograde trans-synaptic effects on rod photoreceptor synapses via matrix-associated proteins. Eur J Neurosci 43:1509-22
Xu, Ying; Orlandi, Cesare; Cao, Yan et al. (2016) The TRPM1 channel in ON-bipolar cells is gated by both the ? and the ?? subunits of the G-protein Go. Sci Rep 6:20940
Tummala, Shanti R; Neinstein, Adam; Fina, Marie E et al. (2014) Localization of Cacna1s to ON bipolar dendritic tips requires mGluR6-related cascade elements. Invest Ophthalmol Vis Sci 55:1483-92
Devi, Sulochana; Markandeya, Yogananda; Maddodi, Nityanand et al. (2013) Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytes. Pigment Cell Melanoma Res 26:348-56
Sulaiman, Pyroja; Xu, Ying; Fina, Marie E et al. (2013) Kir2.4 surface expression and basal current are affected by heterotrimeric G-proteins. J Biol Chem 288:7420-9
Nikonov, Sergei S; Lyubarsky, Arkady; Fina, Marie E et al. (2013) Cones respond to light in the absence of transducin ? subunit. J Neurosci 33:5182-94
Xu, Ying; Dhingra, Anuradha; Fina, Marie E et al. (2012) mGluR6 deletion renders the TRPM1 channel in retina inactive. J Neurophysiol 107:948-57
Dhingra, Anuradha; Ramakrishnan, Hariharasubramanian; Neinstein, Adam et al. (2012) G?3 is required for normal light ON responses and synaptic maintenance. J Neurosci 32:11343-55
Dhingra, Anuradha; Vardi, Noga (2012) ""mGlu Receptors in the Retina"" - WIREs Membrane Transport and Signaling. Wiley Interdiscip Rev Membr Transp Signal 1:641-653
Dhingra, Anuradha; Fina, Marie E; Neinstein, Adam et al. (2011) Autoantibodies in melanoma-associated retinopathy target TRPM1 cation channels of retinal ON bipolar cells. J Neurosci 31:3962-7

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