Inferotemporal cortex (IT) plays a crucial role in object vision as indicated by the fact that injury to it results in profound recognition deficits. The role played by IT in object recognition has been elucidated by research carried out over several decades in macaque monkeys. This has indicated that neurons in IT are pattern selective. Each neuron responds to certain complex images and not others. To gain an understanding of the nature of neuronal pattern selectivity in IT - and hence to cast light on the nature of the neural machinery that underlies visual pattern recognition - is the aim of experiments described in this proposal. Three series of experiments will be carried out. The approach in each case will be to measure the responses of neurons to displays consisting of discrete parts that can be manipulated independently so as to determine how the response to the whole is built up from the responses to the parts. Series 1 will ask whether IT neurons as a population represent, in a dimensionally reduced code, a family of shapes consisting of joined linear segments and having roughly the complexity of alphanumeric characters. Series 2 will ask whether neurons in IT are selective for the arrangement of elements in an image and, if so, whether selectivity is invariant across changes in size and location. Series 3 will ask how neuronal activity in IT represents displays consisting of items in an array, including words and hierarchical stimuli.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY018620-05
Application #
8204924
Study Section
Central Visual Processing Study Section (CVP)
Program Officer
Steinmetz, Michael A
Project Start
2007-12-01
Project End
2013-11-30
Budget Start
2011-12-01
Budget End
2013-11-30
Support Year
5
Fiscal Year
2012
Total Cost
$348,618
Indirect Cost
$111,018
Name
Carnegie-Mellon University
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
052184116
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Meyer, Travis; Walker, Christopher; Cho, Raymond Y et al. (2014) Image familiarization sharpens response dynamics of neurons in inferotemporal cortex. Nat Neurosci 17:1388-94
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Meyer, Travis; Ramachandran, Suchitra; Olson, Carl R (2014) Statistical learning of serial visual transitions by neurons in monkey inferotemporal cortex. J Neurosci 34:9332-7
Meyer, Travis; Olson, Carl R (2011) Statistical learning of visual transitions in monkey inferotemporal cortex. Proc Natl Acad Sci U S A 108:19401-6
Berdyyeva, Tamara K; Olson, Carl R (2011) Relation of ordinal position signals to the expectation of reward and passage of time in four areas of the macaque frontal cortex. J Neurophysiol 105:2547-59
Berdyyeva, Tamara K; Olson, Carl R (2010) Rank signals in four areas of macaque frontal cortex during selection of actions and objects in serial order. J Neurophysiol 104:141-59
Kim, Sung Soo; Sripati, Arun P; Bensmaia, Sliman J (2010) Predicting the timing of spikes evoked by tactile stimulation of the hand. J Neurophysiol 104:1484-96
Sripati, Arun P; Olson, Carl R (2010) Global image dissimilarity in macaque inferotemporal cortex predicts human visual search efficiency. J Neurosci 30:1258-69
Sripati, Arun P; Olson, Carl R (2010) Responses to compound objects in monkey inferotemporal cortex: the whole is equal to the sum of the discrete parts. J Neurosci 30:7948-60
Sripati, Arun P; Olson, Carl R (2009) Representing the forest before the trees: a global advantage effect in monkey inferotemporal cortex. J Neurosci 29:7788-96

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