Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM018974-32
Application #
6695590
Study Section
Special Emphasis Panel (ZRG1-CDF-4 (02))
Program Officer
Shapiro, Bert I
Project Start
1975-01-01
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
32
Fiscal Year
2004
Total Cost
$405,000
Indirect Cost
Name
Harvard University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
047006379
City
Boston
State
MA
Country
United States
Zip Code
02115
Magnotti, Laura M; Goodenough, Daniel A; Paul, David L (2011) Deletion of oligodendrocyte Cx32 and astrocyte Cx43 causes white matter vacuolation, astrocyte loss and early mortality. Glia 59:1064-74
Magnotti, Laura M; Goodenough, Daniel A; Paul, David L (2011) Functional heterotypic interactions between astrocyte and oligodendrocyte connexins. Glia 59:26-34
Altevogt, Bruce M; Paul, David L (2004) Four classes of intercellular channels between glial cells in the CNS. J Neurosci 24:4313-23
Menichella, Daniela M; Goodenough, Daniel A; Sirkowski, Erich et al. (2003) Connexins are critical for normal myelination in the CNS. J Neurosci 23:5963-73
Altevogt, Bruce M; Kleopa, Kleopas A; Postma, Friso R et al. (2002) Connexin29 is uniquely distributed within myelinating glial cells of the central and peripheral nervous systems. J Neurosci 22:6458-70
Bruzzone, R; White, T W; Paul, D L (1994) Expression of chimeric connexins reveals new properties of the formation and gating behavior of gap junction channels. J Cell Sci 107 ( Pt 4):955-67
Bruzzone, R; White, T W; Scherer, S S et al. (1994) Null mutations of connexin32 in patients with X-linked Charcot-Marie-Tooth disease. Neuron 13:1253-60
Musil, L S; Goodenough, D A (1993) Multisubunit assembly of an integral plasma membrane channel protein, gap junction connexin43, occurs after exit from the ER. Cell 74:1065-77
Bruzzone, R; Haefliger, J A; Gimlich, R L et al. (1993) Connexin40, a component of gap junctions in vascular endothelium, is restricted in its ability to interact with other connexins. Mol Biol Cell 4:7-20
Flint, K K; Rosbash, M; Hall, J C (1993) Transfer of dye among salivary gland cells is not affected by genetic variations of the period clock gene in Drosophila melanogaster. J Membr Biol 136:333-42

Showing the most recent 10 out of 30 publications