Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM022807-21
Application #
2173983
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1976-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
21
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Massachusetts Amherst
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
153223151
City
Amherst
State
MA
Country
United States
Zip Code
01003

  Publications

Kirillov, Stanislav V; Wower, Jacek; Hixson, Stephen S et al. (2002) Transit of tRNA through the Escherichia coli ribosome: cross-linking of the 3' end of tRNA to ribosomal proteins at the P and E sites. FEBS Lett 514:60-6
Maguire, B A; Manuilov, A V; Zimmermann, R A (2001) Differential effects of replacing Escherichia coli ribosomal protein L27 with its homologue from Aquifex aeolicus. J Bacteriol 183:6565-72
Wower, J; Kirillov, S V; Wower, I K et al. (2000) Transit of tRNA through the Escherichia coli ribosome. Cross-linking of the 3' end of tRNA to specific nucleotides of the 23 S ribosomal RNA at the A, P, and E sites. J Biol Chem 275:37887-94
Wower, I K; Wower, J; Zimmermann, R A (1998) Ribosomal protein L27 participates in both 50 S subunit assembly and the peptidyl transferase reaction. J Biol Chem 273:19847-52
O'Connor, M; Thomas, C L; Zimmermann, R A et al. (1997) Decoding fidelity at the ribosomal A and P sites: influence of mutations in three different regions of the decoding domain in 16S rRNA. Nucleic Acids Res 25:1185-93
Rosen, K V; Zimmerman, R A (1997) Photoaffinity labeling of 30S-subunit proteins S7 and S11 by 4-thiouridine-substituted tRNA(Phe) situated at the P site of Escherichia coli ribosomes. RNA 3:1028-36
Kalurachchi, K; Uma, K; Zimmermann, R A et al. (1997) Structural features of the binding site for ribosomal protein S8 in Escherichia coli 16S rRNA defined using NMR spectroscopy. Proc Natl Acad Sci U S A 94:2139-44
Wower, J; Wower, I K; Kirillov, S V et al. (1995) Peptidyl transferase and beyond. Biochem Cell Biol 73:1041-7
Wower, J; Hixson, S S; Sylvers, L A et al. (1994) Synthesis of 2,6-diazido-9-(beta-D-ribofuranosyl)purine 3',5'-bisphosphate: incorporation into transfer RNA and photochemical labeling of Escherichia coli ribosomes. Bioconjug Chem 5:158-61
Wower, J; Rosen, K V; Hixson, S S et al. (1994) Recombinant photoreactive tRNA molecules as probes for cross-linking studies. Biochimie 76:1235-46

Showing the most recent 10 out of 25 publications