Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM027870-17
Application #
2175021
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1980-04-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Biochemistry
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Craig, Elizabeth A (2018) Hsp70 at the membrane: driving protein translocation. BMC Biol 16:11
Schilke, Brenda A; Ciesielski, Szymon J; Ziegelhoffer, Thomas et al. (2017) Broadening the functionality of a J-protein/Hsp70 molecular chaperone system. PLoS Genet 13:e1007084
Dutkiewicz, Rafal; Nowak, Malgorzata; Craig, Elizabeth A et al. (2017) Fe-S Cluster Hsp70 Chaperones: The ATPase Cycle and Protein Interactions. Methods Enzymol 595:161-184
Ciesielski, Szymon J; Craig, Elizabeth A (2017) Posttranslational control of the scaffold for Fe-S cluster biogenesis as a compensatory regulatory mechanism. Curr Genet 63:51-56
Craig, Elizabeth A; Marszalek, Jaroslaw (2017) How Do J-Proteins Get Hsp70 to Do So Many Different Things? Trends Biochem Sci 42:355-368
Lee, Kanghyun; Sharma, Ruchika; Shrestha, Om Kumar et al. (2016) Dual interaction of the Hsp70 J-protein cochaperone Zuotin with the 40S and 60S ribosomal subunits. Nat Struct Mol Biol 23:1003-1010
Delewski, Wojciech; Paterkiewicz, Bogumi?a; Manicki, Mateusz et al. (2016) Iron-Sulfur Cluster Biogenesis Chaperones: Evidence for Emergence of Mutational Robustness of a Highly Specific Protein-Protein Interaction. Mol Biol Evol 33:643-56
Ciesielski, Szymon J; Schilke, Brenda; Marszalek, Jaroslaw et al. (2016) Protection of scaffold protein Isu from degradation by the Lon protease Pim1 as a component of Fe-S cluster biogenesis regulation. Mol Biol Cell 27:1060-8
Schmitz-Abe, Klaus; Ciesielski, Szymon J; Schmidt, Paul J et al. (2015) Congenital sideroblastic anemia due to mutations in the mitochondrial HSP70 homologue HSPA9. Blood 126:2734-8
Yu, Hyun Young; Ziegelhoffer, Thomas; Craig, Elizabeth A (2015) Functionality of Class A and Class B J-protein co-chaperones with Hsp70. FEBS Lett 589:2825-30

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