Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM030375-14
Application #
2175791
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1981-07-01
Project End
1997-06-30
Budget Start
1994-07-01
Budget End
1997-06-30
Support Year
14
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Carnegie-Mellon University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
052184116
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Li, X Y; McClure, W R (1998) Stimulation of open complex formation by nicks and apurinic sites suggests a role for nucleation of DNA melting in Escherichia coli promoter function. J Biol Chem 273:23558-66
Li, X Y; McClure, W R (1998) Characterization of the closed complex intermediate formed during transcription initiation by Escherichia coli RNA polymerase. J Biol Chem 273:23549-57
Schaefer, K L; McClure, W R (1997) Antisense RNA control of gene expression in bacteriophage P22. II. Kinetic mechanism and cation specificity of the pairing reaction. RNA 3:157-74
Schaefer, K L; McClure, W R (1997) Antisense RNA control of gene expression in bacteriophage P22. I. Structures of sar RNA and its target, ant mRNA. RNA 3:141-56
Li, M; McClure, W R; Susskind, M M (1997) Changing the mechanism of transcriptional activation by phage lambda repressor. Proc Natl Acad Sci U S A 94:3691-6
Yee, Y C; Kisslinger, B; Yu, V L et al. (1996) A mechanism of rifamycin inhibition and resistance in Pseudomonas aeruginosa. J Antimicrob Chemother 38:133-7
Su, T T; McClure, W R (1994) Selective binding of Escherichia coli RNA polymerase to topoisomers of minicircles carrying the TAC16 and TAC17 promoters. J Biol Chem 269:13511-21
Goodrich, J A; McClure, W R (1992) Regulation of open complex formation at the Escherichia coli galactose operon promoters. Simultaneous interaction of RNA polymerase, gal repressor and CAP/cAMP. J Mol Biol 224:15-29
Goodrich, J A; McClure, W R (1991) Competing promoters in prokaryotic transcription. Trends Biochem Sci 16:394-7
Goodrich, J A; Schwartz, M L; McClure, W R (1990) Searching for and predicting the activity of sites for DNA binding proteins: compilation and analysis of the binding sites for Escherichia coli integration host factor (IHF). Nucleic Acids Res 18:4993-5000

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