Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM035955-11
Application #
2178159
Study Section
Molecular Biology Study Section (MBY)
Project Start
1986-01-01
Project End
1997-11-30
Budget Start
1996-09-01
Budget End
1997-11-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Irvine
Department
Biochemistry
Type
Schools of Medicine
DUNS #
161202122
City
Irvine
State
CA
Country
United States
Zip Code
92697
Cote, Colette A; Greer, Chris L; Peculis, Brenda A (2002) Dynamic conformational model for the role of ITS2 in pre-rRNA processing in yeast. RNA 8:786-97
Peculis, B A; Greer, C L (1998) The structure of the ITS2-proximal stem is required for pre-rRNA processing in yeast. RNA 4:1610-22
Phizicky, E M; Greer, C L (1993) Pre-tRNA splicing: variation on a theme or exception to the rule? Trends Biochem Sci 18:31-4
Westaway, S K; Belford, H G; Apostol, B L et al. (1993) Novel activity of a yeast ligase deletion polypeptide. Evidence for GTP-dependent tRNA splicing. J Biol Chem 268:2435-43
Belford, H G; Westaway, S K; Abelson, J et al. (1993) Multiple nucleotide cofactor use by yeast ligase in tRNA splicing. Evidence for independent ATP- and GTP-binding sites. J Biol Chem 268:2444-50
Haselbeck, R C; Greer, C L (1993) Minimum intron requirements for tRNA splicing and nuclear transport in Xenopus oocytes. Biochemistry 32:8575-81
Shapero, M H; Greer, C L (1992) Exon sequence and structure requirements for tRNA splicing in Saccharomyces cerevisiae. Biochemistry 31:2359-67
Shapero, M H; Greer, C L (1991) Conformational transition required for efficient splicing of transcripts from hybrid lambda promoter yeast tRNA gene fusion. Biochemistry 30:6465-75
Szekely, E; Belford, H G; Greer, C L (1988) Intron sequence and structure requirements for tRNA splicing in Saccharomyces cerevisiae. J Biol Chem 263:13839-47
Apostol, B; Greer, C L (1988) Copy number and stability of yeast 2 mu-based plasmids carrying a transcription-conditional centromere. Gene 67:59-68