Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM040993-03
Application #
3298974
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1988-12-01
Project End
1993-11-30
Budget Start
1990-12-01
Budget End
1991-11-30
Support Year
3
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Harvard University
Department
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Liu, Xueqiao; De Wulf, Peter (2004) Probing the ArcA-P modulon of Escherichia coli by whole genome transcriptional analysis and sequence recognition profiling. J Biol Chem 279:12588-97
Kwon, Ohsuk; Georgellis, Dimitris; Lin, Edmund C C (2003) Rotational on-off switching of a hybrid membrane sensor kinase Tar-ArcB in Escherichia coli. J Biol Chem 278:13192-5
Nunez, Maria Felisa; Kwon, Ohsuk; Wilson, T Hastings et al. (2002) Transport of L-Lactate, D-Lactate, and glycolate by the LldP and GlcA membrane carriers of Escherichia coli. Biochem Biophys Res Commun 290:824-9
Echave, Pedro; Esparza-Ceron, M Angel; Cabiscol, Elisa et al. (2002) DnaK dependence of mutant ethanol oxidoreductases evolved for aerobic function and protective role of the chaperone against protein oxidative damage in Escherichia coli. Proc Natl Acad Sci U S A 99:4626-31
De Wulf, Peter; McGuire, Abigail M; Liu, Xueqiao et al. (2002) Genome-wide profiling of promoter recognition by the two-component response regulator CpxR-P in Escherichia coli. J Biol Chem 277:26652-61
Georgellis, D; Kwon, O; Lin, E C (2001) Quinones as the redox signal for the arc two-component system of bacteria. Science 292:2314-6
Georgellis, D; Kwon, O; Lin, E C et al. (2001) Redox signal transduction by the ArcB sensor kinase of Haemophilus influenzae lacking the PAS domain. J Bacteriol 183:7206-12
Pernestig, A K; Melefors, O; Georgellis, D (2001) Identification of UvrY as the cognate response regulator for the BarA sensor kinase in Escherichia coli. J Biol Chem 276:225-31
Membrillo-Hernandez, J; Echave, P; Cabiscol, E et al. (2000) Evolution of the adhE gene product of Escherichia coli from a functional reductase to a dehydrogenase. Genetic and biochemical studies of the mutant proteins. J Biol Chem 275:33869-75
Kwon, O; Georgellis, D; Lin, E C (2000) Phosphorelay as the sole physiological route of signal transmission by the arc two-component system of Escherichia coli. J Bacteriol 182:3858-62

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