Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM042230-06
Application #
2181282
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1991-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
Schools of Pharmacy
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Owen, Ryan P; Badagnani, Ilaria; Giacomini, Kathleen M (2006) Molecular determinants of specificity for synthetic nucleoside analogs in the concentrative nucleoside transporter, CNT2. J Biol Chem 281:26675-82
Badagnani, I; Chan, W; Castro, R A et al. (2005) Functional analysis of genetic variants in the human concentrative nucleoside transporter 3 (CNT3; SLC28A3). Pharmacogenomics J 5:157-65
Owen, Ryan P; Gray, Jennifer H; Taylor, Travis R et al. (2005) Genetic analysis and functional characterization of polymorphisms in the human concentrative nucleoside transporter, CNT2. Pharmacogenet Genomics 15:83-90
Gray, Jennifer H; Owen, Ryan P; Giacomini, Kathleen M (2004) The concentrative nucleoside transporter family, SLC28. Pflugers Arch 447:728-34
Mangravite, Lara M; Badagnani, Ilaria; Giacomini, Kathleen M (2003) Nucleoside transporters in the disposition and targeting of nucleoside analogs in the kidney. Eur J Pharmacol 479:269-81
Mangravite, Lara M; Giacomini, Kathleen M (2003) Sorting of rat SPNT in renal epithelium is independent of N-glycosylation. Pharm Res 20:319-23
Mangravite, Lara M; Xiao, Guangqing; Giacomini, Kathleen M (2003) Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells. Am J Physiol Renal Physiol 284:F902-10
Gerstin, Karin M; Dresser, Mark J; Giacomini, Kathleen M (2002) Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT. Am J Physiol Renal Physiol 283:F344-9
Mangravite, L M; Lipschutz, J H; Mostov, K E et al. (2001) Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line. Am J Physiol Renal Physiol 280:F879-85
Xiao, G; Wang, J; Tangen, T et al. (2001) A novel proton-dependent nucleoside transporter, CeCNT3, from Caenorhabditis elegans. Mol Pharmacol 59:339-48

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