Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM042231-16
Application #
2181286
Study Section
Molecular Biology Study Section (MBY)
Project Start
1981-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
071723621
City
Cambridge
State
MA
Country
United States
Zip Code
02138
Buchanan, Sean M; Schalm, Stefanie S; Maniatis, Tom (2010) Proteolytic processing of protocadherin proteins requires endocytosis. Proc Natl Acad Sci U S A 107:17774-9
Ribich, Scott; Tasic, Bosiljka; Maniatis, Tom (2006) Identification of long-range regulatory elements in the protocadherin-alpha gene cluster. Proc Natl Acad Sci U S A 103:19719-24
Ibrahim, El Cherif; Schaal, Thomas D; Hertel, Klemens J et al. (2005) Serine/arginine-rich protein-dependent suppression of exon skipping by exonic splicing enhancers. Proc Natl Acad Sci U S A 102:5002-7
Tasic, Bosiljka; Nabholz, Christoph E; Baldwin, Kristin K et al. (2002) Promoter choice determines splice site selection in protocadherin alpha and gamma pre-mRNA splicing. Mol Cell 10:21-33
Graveley, B R; Hertel, K J; Maniatis, T (2001) The role of U2AF35 and U2AF65 in enhancer-dependent splicing. RNA 7:806-18
Wu, Q; Zhang, T; Cheng, J F et al. (2001) Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. Genome Res 11:389-404
Gaur, R K; Beigelman, L; Haeberli, P et al. (2000) Role of adenine functional groups in the recognition of the 3'-splice-site AG during the second step of pre-mRNA splicing. Proc Natl Acad Sci U S A 97:115-20
Wu, Q; Maniatis, T (2000) Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes. Proc Natl Acad Sci U S A 97:3124-9
Wu, Q; Maniatis, T (1999) A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell 97:779-90
Schaal, T D; Maniatis, T (1999) Selection and characterization of pre-mRNA splicing enhancers: identification of novel SR protein-specific enhancer sequences. Mol Cell Biol 19:1705-19

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