The primary goal of the proposed research is to advance our understanding of non-pharmacologic control of pain from burn injuries and other etiologies by applying state-of-the-art advances in immersive virtual reality (VR) technology. The significance of an effective psychological treatment for controlling severe burn pain includes reducing: (1) pain and suffering, (2) the length of hospital stay and associated costs, (3) the sid effects and diversion potential of opioid analgesics, and (4) the risk of developing chronic pain. The innovation involved in this project involves applying a relatively new technology, immersive VR to intensive treatment environments that previously presented too many challenges for this analgesic approach. Specifically, VR will be used in wet-wound wound treatments settings with children and adults that have extensive dressing changes and very large burn injuries. The participants from this study will involve children and adults, many of whom represent underserved minorities. The approach of this application will be to conduct a randomized controlled trial that compares high-immersion VR, with low-immersion VR and standard control conditions. 160 participants from two major regional burn centers will undergo all of their wound care sessions using either VR software specifically designed for burn care, nature pictures and sounds or standard treatment as usual. Participant pain relief will be measured by pain ratings on a number of dimensions and we have hypothesized that participants in the high-immersion VR group will report less pain than the two comparison groups. We will also investigate the impact of VR on a number of other relevant variables such as pain medication use and length of hospitalization. Participants will be followed at 6 and 12-month follow-up periods to investigate the impact of VR on long term pain ratings. We anticipate that the findings will have implications for controlling high levels of acute pain with safe, non-additive treatment approaches that facilitate the overall care and outcome of people who have survived severe burn injuries.

Public Health Relevance

This project will investigate innovative applications of immersive virtual reality (VR) for controlling unusually severe burn pain in intensive care treatment settings. A randomized controlled trial will be completed to compare high-immersion VR for pain control during burn dressing changes with control groups in pediatric and adult participants. The significance of the potential findings will be developing safe, not-addictive treatments for unusually severe pain, reducing associated costs of care, and improving outcome after one of the most challenging forms of physical trauma.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM042725-22
Application #
9116175
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Somers, Scott D
Project Start
1990-04-01
Project End
2019-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
22
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Washington
Department
Physical Medicine & Rehab
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Frey, David P; Bauer, Melissa E; Bell, Carrie L et al. (2018) Virtual Reality Analgesia in Labor: The VRAIL Pilot Study-A Preliminary Randomized Controlled Trial Suggesting Benefit of Immersive Virtual Reality Analgesia in Unmedicated Laboring Women. Anesth Analg :
Patterson, David R; Hoffer, Christine; Jensen, Mark P et al. (2018) KETAMINE AS A POSSIBLE MODERATOR OF HYPNOTIZABILITY: A FEASIBILITY STUDY. Int J Clin Exp Hypn 66:298-307
Wiechman, Shelley; Hoyt, Michael A; Patterson, David R (2018) Using a Biopsychosocial Model to Understand Long-Term Outcomes in Persons With Burn Injuries. Arch Phys Med Rehabil :
Atzori, Barbara; Lauro Grotto, Rosapia; Giugni, Andrea et al. (2018) Virtual Reality Analgesia for Pediatric Dental Patients. Front Psychol 9:2265
Khadra, Christelle; Ballard, Ariane; Déry, Johanne et al. (2018) Projector-based virtual reality dome environment for procedural pain and anxiety in young children with burn injuries: a pilot study. J Pain Res 11:343-353
Flores, Araceli; Linehan, Marsha M; Todd, S Rob et al. (2018) The Use of Virtual Reality to Facilitate Mindfulness Skills Training in Dialectical Behavioral Therapy for Spinal Cord Injury: A Case Study. Front Psychol 9:531
Soltani, Maryam; Drever, Sydney A; Hoffman, Hunter G et al. (2018) Virtual reality analgesia for burn joint flexibility: A randomized controlled trial. Rehabil Psychol 63:487-494
Elkins, Ralph L; Richards, Todd L; Nielsen, Robert et al. (2017) The Neurobiological Mechanism of Chemical Aversion (Emetic) Therapy for Alcohol Use Disorder: An fMRI Study. Front Behav Neurosci 11:182
Navarro-Haro, María V; López-Del-Hoyo, Yolanda; Campos, Daniel et al. (2017) Meditation experts try Virtual Reality Mindfulness: A pilot study evaluation of the feasibility and acceptability of Virtual Reality to facilitate mindfulness practice in people attending a Mindfulness conference. PLoS One 12:e0187777
Gomez, Jocelyn; Hoffman, Hunter G; Bistricky, Steven L et al. (2017) The Use of Virtual Reality Facilitates Dialectical Behavior Therapy® ""Observing Sounds and Visuals"" Mindfulness Skills Training Exercises for a Latino Patient with Severe Burns: A Case Study. Front Psychol 8:1611

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