Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM046331-06
Application #
2183814
Study Section
Molecular Biology Study Section (MBY)
Project Start
1991-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Emory University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
O'Rourke, Thomas W; Reines, Daniel (2016) Determinants of Amyloid Formation for the Yeast Termination Factor Nab3. PLoS One 11:e0150865
Loya, Travis J; Reines, Daniel (2016) Recent advances in understanding transcription termination by RNA polymerase II. F1000Res 5:
O'Rourke, Thomas W; Loya, Travis J; Head, PamelaSara E et al. (2015) Amyloid-like assembly of the low complexity domain of yeast Nab3. Prion 9:34-47
Arndt, Karen M; Reines, Daniel (2015) Termination of Transcription of Short Noncoding RNAs by RNA Polymerase II. Annu Rev Biochem 84:381-404
Loya, Travis J; O'Rourke, Thomas W; Reines, Daniel (2013) Yeast Nab3 protein contains a self-assembly domain found in human heterogeneous nuclear ribonucleoprotein-C (hnRNP-C) that is necessary for transcription termination. J Biol Chem 288:2111-7
Loya, Travis J; O'Rourke, Thomas W; Degtyareva, Natalya et al. (2013) A network of interdependent molecular interactions describes a higher order Nrd1-Nab3 complex involved in yeast transcription termination. J Biol Chem 288:34158-67
Loya, Travis J; O'Rourke, Thomas W; Reines, Daniel (2012) A genetic screen for terminator function in yeast identifies a role for a new functional domain in termination factor Nab3. Nucleic Acids Res 40:7476-91
Reines, Daniel (2012) Decapping goes nuclear. Mol Cell 46:241-2
Jenks, M Harley; O'Rourke, Thomas W; Reines, Daniel (2008) Properties of an intergenic terminator and start site switch that regulate IMD2 transcription in yeast. Mol Cell Biol 28:3883-93
Kopcewicz, Katarzyna A; O'Rourke, Thomas W; Reines, Daniel (2007) Metabolic regulation of IMD2 transcription and an unusual DNA element that generates short transcripts. Mol Cell Biol 27:2821-9

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