Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM046503-06
Application #
2183999
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1991-09-01
Project End
1997-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Trinity University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
City
San Antonio
State
TX
Country
United States
Zip Code
78212
Cheng, Qing-Qing; Deng, Yongming; Lankelma, Marianne et al. (2017) Cycloaddition reactions of enoldiazo compounds. Chem Soc Rev 46:5425-5443
Xu, Xinfang; Deng, Yongming; Yim, David N et al. (2015) Enantioselective cis-?-lactam synthesis by intramolecular C-H functionalization from enoldiazoacetamides and derivative donor-acceptor cyclopropenes. Chem Sci 6:2196-2201
Xu, Xinfang; Wang, Xiangbo; Zavalij, Peter Y et al. (2015) Straightforward access to the [3.2.2]nonatriene structural framework via intramolecular cyclopropenation/Buchner reaction/Cope rearrangement cascade. Org Lett 17:790-3
Xu, Xinfang; Doyle, Michael P (2014) The [3 + 3]-cycloaddition alternative for heterocycle syntheses: catalytically generated metalloenolcarbenes as dipolar adducts. Acc Chem Res 47:1396-405
Xu, Xinfang; Xu, Xichen; Zavalij, Peter Y et al. (2013) Dirhodium(II)-catalyzed formal [3+2+1]-annulation of azomethine imines with two molecules of a diazo ketone. Chem Commun (Camb) 49:2762-4
Xu, Xinfang; Zavalij, Peter Y; Hu, Wenhao et al. (2013) Vinylogous reactivity of enol diazoacetates with donor-acceptor substituted hydrazones. Synthesis of substituted pyrazole derivatives. J Org Chem 78:1583-8
Xu, Xichen; Qian, Yu; Zavalij, Peter Y et al. (2013) Highly selective catalyst-dependent competitive 1,2-CýýýC, -OýýýC, and -NýýýC migrations from ýý-methylene-ýý-silyloxy-ýý-amido-ýý-diazoacetates. J Am Chem Soc 135:1244-7
Qian, Yu; Zavalij, Peter J; Hu, Wenhao et al. (2013) Bicyclic pyrazolidinone derivatives from diastereoselective catalytic [3 + 3]-cycloaddition reactions of enoldiazoacetates with azomethine imines. Org Lett 15:1564-7
Xu, Xinfang; Zavalij, Peter Y; Doyle, Michael P (2013) Highly enantioselective dearomatizing formal [3+3] cycloaddition reactions of N-acyliminopyridinium ylides with electrophilic enol carbene intermediates. Angew Chem Int Ed Engl 52:12664-8
Shanahan, Charles S; Truong, Phong; Mason, Savannah M et al. (2013) Diazoacetoacetate enones for the synthesis of diverse natural product-like scaffolds. Org Lett 15:3642-5

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