Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
7R01GM046749-06
Application #
2392161
Study Section
Metallobiochemistry Study Section (BMT)
Project Start
1992-02-01
Project End
2000-03-31
Budget Start
1996-08-01
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Oregon Graduate Institute Science & Tech
Department
Chemistry
Type
Other Domestic Higher Education
DUNS #
City
Beaverton
State
OR
Country
United States
Zip Code
97006
Kempner, Ellis S; Whittaker, James W; Miller, Jay H (2010) Radiation inactivation of galactose oxidase, a monomeric enzyme with a stable free radical. Protein Sci 19:236-41
Lee, Yuk-Ki; Whittaker, Mei M; Whittaker, James W (2008) The electronic structure of the Cys-Tyr(*) free radical in galactose oxidase determined by EPR spectroscopy. Biochemistry 47:6637-49
Tkac, Jan; Whittaker, James W; Ruzgas, Tautgirdas (2007) The use of single walled carbon nanotubes dispersed in a chitosan matrix for preparation of a galactose biosensor. Biosens Bioelectron 22:1820-4
Whittaker, James W (2007) Selective isotopic labeling of recombinant proteins using amino acid auxotroph strains. Methods Mol Biol 389:175-88
Whittaker, Mei M; Whittaker, James W (2006) Streptomyces coelicolor oxidase (SCO2837p): a new free radical metalloenzyme secreted by Streptomyces coelicolor A3(2). Arch Biochem Biophys 452:108-18
Whittaker, Mei M; Whittaker, James W (2005) Construction and characterization of Pichia pastoris strains for labeling aromatic amino acids in recombinant proteins. Protein Expr Purif 41:266-74
Shleev, Sergey; Tkac, Jan; Christenson, Andreas et al. (2005) Direct electron transfer between copper-containing proteins and electrodes. Biosens Bioelectron 20:2517-54
Whittaker, James W (2005) The radical chemistry of galactose oxidase. Arch Biochem Biophys 433:227-39
Minasian, Stefan G; Whittaker, Mei M; Whittaker, James W (2004) Stereoselective hydrogen abstraction by galactose oxidase. Biochemistry 43:13683-93
Whittaker, Mei M; Whittaker, James W (2003) Cu(I)-dependent biogenesis of the galactose oxidase redox cofactor. J Biol Chem 278:22090-101

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