Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM047017-01
Application #
3306561
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1992-02-01
Project End
1992-09-29
Budget Start
1992-02-01
Budget End
1992-09-29
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Origanti, S; Cai, S-r; Munir, A Z et al. (2013) Synthetic lethality of Chk1 inhibition combined with p53 and/or p21 loss during a DNA damage response in normal and tumor cells. Oncogene 32:577-88
Huh, Jiwon; Piwnica-Worms, Helen (2013) CRL4(CDT2) targets CHK1 for PCNA-independent destruction. Mol Cell Biol 33:213-26
Honaker, Y; Piwnica-Worms, H (2010) Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction. Oncogene 29:3324-34
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Kang, Tiebang; Wei, Yongkun; Honaker, Yuchi et al. (2008) GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers. Cancer Cell 13:36-47
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