Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM050778-03
Application #
2188839
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1993-12-01
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Mcmaster University
Department
Type
DUNS #
City
Hamilton
State
ON
Country
Canada
Zip Code
L8 3-Z5

  Publications

Zeidler, Johannes; Sayer, Brian G; Spenser, Ian D (2003) Biosynthesis of vitamin B1 in yeast. Derivation of the pyrimidine unit from pyridoxine and histidine. Intermediacy of urocanic acid. J Am Chem Soc 125:13094-105
Zeidler, Johannes; Gupta, Ram Nath; Sayer, Brian G et al. (2003) Biosynthesis of Vitamin B(6) in yeast. Incorporation pattern of trioses. J Org Chem 68:3486-93
Zeidler, Johannes; Ullah, Nisar; Gupta, Ram Nath et al. (2002) 2'-hydroxypyridoxol, a biosynthetic precursor of vitamins B(6) and B(1) in yeast. J Am Chem Soc 124:4542-3
Gupta, R N; Hemscheidt, T; Sayer, B G et al. (2001) Biosynthesis of vitamin B(6) in yeast: incorporation pattern of glucose. J Am Chem Soc 123:11353-9
Hill, R E; Himmeldirk, K; Kennedy, I A et al. (1996) The biogenetic anatomy of vitamin B6. A 13C NMR investigation of the biosynthesis of pyridoxol in Escherichia coli. J Biol Chem 271:30426-35
Spenser, I D; Hill, R E (1995) The biosynthesis of pyridoxine. Nat Prod Rep 12:555-65