Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM051279-03
Application #
2189686
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1994-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Hur, Stella K; Freschi, Andrea; Ideraabdullah, Folami et al. (2016) Humanized H19/Igf2 locus reveals diverged imprinting mechanism between mouse and human and reflects Silver-Russell syndrome phenotypes. Proc Natl Acad Sci U S A 113:10938-43
Ginart, Paul; Kalish, Jennifer M; Jiang, Connie L et al. (2016) Visualizing allele-specific expression in single cells reveals epigenetic mosaicism in an H19 loss-of-imprinting mutant. Genes Dev 30:567-78
Plasschaert, Robert N; Bartolomei, Marisa S (2015) Tissue-specific regulation and function of Grb10 during growth and neuronal commitment. Proc Natl Acad Sci U S A 112:6841-7
Zhong, Cuiqing; Yin, Qi; Xie, Zhenfei et al. (2015) CRISPR-Cas9-Mediated Genetic Screening in Mice with Haploid Embryonic Stem Cells Carrying a Guide RNA Library. Cell Stem Cell 17:221-32
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Venkatraman, Aparna; He, Xi C; Thorvaldsen, Joanne L et al. (2013) Maternal imprinting at the H19-Igf2 locus maintains adult haematopoietic stem cell quiescence. Nature 500:345-9
Abramowitz, Lara K; Bartolomei, Marisa S (2012) Genomic imprinting: recognition and marking of imprinted loci. Curr Opin Genet Dev 22:72-8
Wu, Xin; Goodyear, Shaun M; Abramowitz, Lara K et al. (2012) Fertile offspring derived from mouse spermatogonial stem cells cryopreserved for more than 14 years. Hum Reprod 27:1249-59
Hudson, Quanah J; Seidl, Christine I M; Kulinski, Tomasz M et al. (2011) Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo. Dev Biol 353:420-31

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